Evidence map›Paper›PMID 27981012›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2016

Plasmonic Nanoparticles with Quantitatively Controlled Bioconjugation for Photoacoustic Imaging of Live Cancer Cells.

Chao Tian, Wei Qian, Xia Shao, Zhixing Xie, Xu Cheng, Shengchun Liu, Qian Cheng, Bing Liu, Xueding Wang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
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  8. Preparation and Evaluation ofPharmaceuticals (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chao TianDepartment of Biomedical Engineering University of Michigan Ann Arbor MI 48109 USA.
Wei QianIMRA America, Inc Ann Arbor MI 48105 USA.
Xia ShaoDepartment of Radiology University of Michigan Ann Arbor MI 48109 USA.
Zhixing XieDepartment of Radiology University of Michigan Ann Arbor MI 48109 USA.
Xu ChengDepartment of Urology University of Michigan Ann Arbor MI 48109 USA.
Shengchun LiuCollege of Physical Science and Technology Heilongjiang University Harbin 150080 China.
Qian ChengInstitute of Acoustics Tongji University Shanghai 200092 China.
Bing LiuIMRA America, Inc Ann Arbor MI 48105 USA.
Xueding WangDepartment of Biomedical Engineering University of Michigan Ann Arbor MI 48109 USA; Department of Radiology University of Michigan Ann Arbor MI 48109 USA; Institute of Acoustics Tongji University Shanghai 200092 China.

Funding

Physiology of Inflammatory Arthritis in High ResolutionR01AR060350 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, XUEDING · 2011 to 2021
$6.0M
Photonic Nanosonophores for Functional and Structural ImagingR01CA186769 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOPELMAN, RAOUL, WANG, XUEDING · 2014 to 2018
$1.6M
NCI NIH HHS R01 CA186769NIAMS NIH HHS R01 AR060350
6 · The paper itself

Abstract

Detection and imaging of single cancer cells is critical for cancer diagnosis and understanding of cellular dynamics. Photoacoustic imaging (PAI) provides a potential tool for the study of cancer cell dynamics, but faces the challenge that most cancer cells lack sufficient endogenous contrast. Here, a type of colloidal gold nanoparticles (AuNPs) are physically fabricated and are precisely functionalized with quantitative amounts of functional ligands (i.e., polyethyleneglycol (PEG) and (Arginine(R)-Glycine(G)-Aspartic(D))

Indexed as

cancer cellsphotoacoustic imagingplasmonic nanoparticlesquantitative bioconjugation

Identifiers

PMID27981012
PMCPMC5157183

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.