Evidence map›Paper›PMID 27981009›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2016

Guidable Thermophoretic Janus Micromotors Containing Gold Nanocolorifiers for Infrared Laser Assisted Tissue Welding.

Wenping He, Johannes Frueh, Narisu Hu, Liping Liu, Meiyu Gai, Qiang He

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Rapid Blood Clot Removal via Remote Delamination and Magnetization of Clot Debris.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  2. Review
  3. Article
  4. Active Micro/Nanoparticles in Colloidal Microswarms.Nanomaterials (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Ultrasmall FeNanomaterials (Basel, Switzerland) · 2023
    Article
  7. Review
  8. Twin-Engine Janus Supramolecular Nanomotors with Counterbalanced Motion.Journal of the American Chemical Society · 2022
    Article
  9. Nanoswimmers Based on Capped Janus Nanospheres.Materials (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Heat-Mediated Optical Manipulation.Chemical reviews · 2022
    Review
  12. Mechanically Optimize T Cells Activation by Spiky Nanomotors.Frontiers in bioengineering and biotechnology · 2022
    Article
  13. Medical Micro/Nanorobots in Precision Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Light-Ultrasound Driven Collective "Firework" Behavior of Nanomotors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenping HeKey Laboratory of Microsystems and Microstructures Manufacturing Ministry of Education Micro/Nano Technology Research Centre Harbin Institute of Technology Yikuang Street 2 Harbin 150080 P. R. China.
Johannes FruehKey Laboratory of Microsystems and Microstructures Manufacturing Ministry of Education Micro/Nano Technology Research Centre Harbin Institute of Technology Yikuang Street 2 Harbin 150080 P. R. China.
Narisu HuKey Laboratory of Microsystems and Microstructures Manufacturing Ministry of Education Micro/Nano Technology Research Centre Harbin Institute of Technology Yikuang Street 2 Harbin 150080 P. R. China.
Liping LiuMental Health Centre 1st Affiliated Hospital of Harbin Medical University Harbin 150001 P. R. China.
Meiyu GaiKey Laboratory of Microsystems and Microstructures Manufacturing Ministry of Education Micro/Nano Technology Research Centre Harbin Institute of Technology Yikuang Street 2 Harbin 150080 P. R. China; Queen Mary University of London School of Engineering and Materials Science Mile End, Eng, 215 London E1 4NS UK.
Qiang HeKey Laboratory of Microsystems and Microstructures Manufacturing Ministry of Education Micro/Nano Technology Research Centre Harbin Institute of Technology Yikuang Street 2 Harbin 150080 P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current wound sealing systems such as nanoparticle-based gluing of tissues allow almost immediate wound sealing. The assistance of a laser beam allows the wound sealing with higher controllability due to the collagen fiber melting which is defined by loss of tertiary protein structure and restoration upon cooling. Usually one employs dyes to paint onto the wound, if water absorption bands are absent. In case of strong bleeding or internal wounds such applications are not feasible due to low welding depth in case of water absorption bands, dyes washing off, or the dyes becoming diluted within the wound. One possible solution of these drawbacks is to use autonomously movable particles composing of biocompatible gold and magnetite nanoparticles and biocompatible polyelectrolyte complexes. In this paper a proof of principle study is presented on the utilization of thermophoretic Janus particles and capsules employed as dyes for infrared laser-assisted tissue welding. This approach proves to be efficient in sealing the wound on the mouse in vivo. The temperature measurement of single particle level proves successful photothermal heating, while the mechanical characterizations of welded liver, skin, and meat confirm mechanical restoration of the welded biological samples.

Indexed as

diffusion based temperature measurementJanus capsulelaser tissue weldingpolyelectrolyte multilayerthermophoretics

Identifiers

PMID27981009
PMCPMC5157175

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.