Evidence map›Paper›PMID 27981006›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2016

Enabling the Triplet of Tetraphenylethene to Sensitize the Excited State of Europium(III) for Protein Detection and Time-Resolved Luminescence Imaging.

Zece Zhu, Bo Song, Jingli Yuan, Chuluo Yang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zece ZhuHubei Collaborative Innovation Center for Advanced Organic Chemical Materials Hubei Key Lab on Organic and Polymeric Optoelectronic Materials Department of Chemistry Wuhan University Wuhan 430072 P. R. China.
Bo SongState Key Laboratory of Fine Chemicals School of Chemistry Dalian University of Technology Dalian 116024 P. R. China.
Jingli YuanState Key Laboratory of Fine Chemicals School of Chemistry Dalian University of Technology Dalian 116024 P. R. China.
Chuluo YangHubei Collaborative Innovation Center for Advanced Organic Chemical Materials Hubei Key Lab on Organic and Polymeric Optoelectronic Materials Department of Chemistry Wuhan University Wuhan 430072 P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A tetraphenylethene (TPE) group that exhibits aggregation-induced emission is incorporated into the ligand of a Eu(III) complex (TPEEu) to sensitize the excited state of Eu(III). In steady-state measurements, TPEEu exhibits weak luminescence when dissolved in aqueous solutions even at a high concentration level, but emits strong fluorescence of TPE and phosphorescence of Eu(III) upon binding with bovine serum albumin. With a delay time of 0.05 ms and a gate time of 1.0 ms in time-resolved measurements, only phosphorescent emission of Eu(III) is observed with a high on/off ratio. Moreover, this probe is successfully used in time-resolved luminescence imaging to eliminate the background signal from biological autofluorescence without a washing process. This work provides a general strategy in designing Ln(III) complexes for detecting a broad range of biological molecules.

Indexed as

europium complexluminescence probeprotein detectiontime‐resolved imaging

Identifiers

PMID27981006
PMCPMC5157173

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.