Evidence map›Paper›PMID 27980906›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2015

A Phosphorescent Iridium(III) Complex-Modified Nanoprobe for Hypoxia Bioimaging Via Time-Resolved Luminescence Microscopy.

Wen Lv, Tianshe Yang, Qi Yu, Qiang Zhao, Kenneth Yin Zhang, Hua Liang, Shujuan Liu, Fuyou Li, Wei Huang

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 103 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. A Cyclodextrin-Hosted Ir(III) Complex for Ratiometric Mapping of Tumor Hypoxia In Vivo.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
  6. Review
  7. Article
  8. Hypoxia-active nanoparticles used in tumor theranostic.International journal of nanomedicine · 2019
    Review
  9. Review
  10. Review
  11. Article
  12. Conjugated polymer nanomaterials for theranostics.Acta pharmacologica Sinica · 2017
    Review
  13. Article
  14. Article
  15. Luminescent Probe Based Techniques for Hypoxia Imaging.Journal of nanomedicine research · 2017
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Wen LvKey Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing University of Posts and Telecommunications Nanjing 210023 P.R. China.
Tianshe YangKey Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing University of Posts and Telecommunications Nanjing 210023 P.R. China.
Qi YuKey Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing University of Posts and Telecommunications Nanjing 210023 P.R. China.
Qiang ZhaoKey Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing University of Posts and Telecommunications Nanjing 210023 P.R. China.
Kenneth Yin ZhangKey Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing University of Posts and Telecommunications Nanjing 210023 P.R. China.
Hua LiangKey Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing University of Posts and Telecommunications Nanjing 210023 P.R. China.
Shujuan LiuKey Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing University of Posts and Telecommunications Nanjing 210023 P.R. China.
Fuyou LiDepartment of Chemistry and the State Key Laboratory of Molecular Engineering of Polymers and Institute of Biomedicine Science Fudan University Shanghai 200433 P.R. China.
Wei HuangKey Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing Tech University (NanjingTech) Nanjing 211816 P.R. China.
Nanjing University of Posts and Telecommunications · CNThe Synergetic Innovation Center for Advanced Materials · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen plays a crucial role in many biological processes. Accurate monitoring of oxygen level is important for diagnosis and treatment of diseases. Autofluorescence is an unavoidable interference in luminescent bioimaging, so that an amount of research work has been devoted to reducing background autofluorescence. Herein, a phosphorescent iridium(III) complex-modified nanoprobe is developed, which can monitor oxygen concentration and also reduce autofluorescence under both downconversion and upconversion channels. The nanoprobe is designed based on the mesoporous silica coated lanthanide-doped upconversion nanoparticles, which contains oxygen-sensitive iridium(III) complex in the outer silica shell. To image intracellular hypoxia without the interferences of autofluorescence, time-resolved luminescent imaging technology and near-infrared light excitation, both of which can reduce autofluorescence effectively, are adopted in this work. Moreover, gradient O

Indexed as

biosensorsenergy transferoxygen nanoprobesphosphorescencetime‐resolved luminescent imaging

Identifiers

PMID27980906
PMCPMC5115315
OpenAlexW1522305543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.