Evidence map›Paper›PMID 27980775›Full record

ArticleImmunity, inflammation and disease2016

Involvement of IL-17A-producing TCR γδ T cells in late protective immunity against pulmonary

Masayuki Umemura, Yuko Okamoto-Yoshida, Ayano Yahagi, Seigo Touyama, Susumu Nakae, Yoichiro Iwakura, Goro Matsuzaki

Open access · goldAbstract read
In one paragraph

Article in Immunity, inflammation and disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Masayuki UmemuraMolecular Microbiology GroupDepartment of Infectious DiseasesTropical Biosphere Research CenterUniversity of the Ryukyus1 SenbaruNishiharaOkinawa903-0213Japan; Department of Host DefenseGraduate School of MedicineUniversity of the Ryukyus1 SenbaruNishiharaOkinawa903-0213Japan.
Yuko Okamoto-YoshidaMolecular Microbiology Group Department of Infectious Diseases Tropical Biosphere Research Center University of the Ryukyus 1 Senbaru Nishihara Okinawa 903-0213 Japan.
Ayano YahagiMolecular Microbiology Group Department of Infectious Diseases Tropical Biosphere Research Center University of the Ryukyus 1 Senbaru Nishihara Okinawa 903-0213 Japan.
Seigo TouyamaMolecular Microbiology GroupDepartment of Infectious DiseasesTropical Biosphere Research CenterUniversity of the Ryukyus1 SenbaruNishiharaOkinawa903-0213Japan; Department of Host DefenseGraduate School of MedicineUniversity of the Ryukyus1 SenbaruNishiharaOkinawa903-0213Japan.
Susumu NakaeLaboratory of Systems Biology Center for Experimental Medicine and Systems Biology Institute of Medical Science University of Tokyo 4-6-1 Shiroganedai Minato-ku Tokyo 108-8639 Japan.
Yoichiro IwakuraDivision of Experimental Animal Immunology Center for Animal Disease Models Research Institute for Biomedical Sciences Tokyo University of Science Chiba 278-0022 Japan.
Goro MatsuzakiMolecular Microbiology GroupDepartment of Infectious DiseasesTropical Biosphere Research CenterUniversity of the Ryukyus1 SenbaruNishiharaOkinawa903-0213Japan; Department of Host DefenseGraduate School of MedicineUniversity of the Ryukyus1 SenbaruNishiharaOkinawa903-0213Japan.
University of the Ryukyus · JPCentral Institute for Experimental Animals · JPTokyo University of Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInterleukin (IL)-17A is a cytokine originally reported to induce neutrophil-mediated inflammation and anti-microbial activity. The CD4

methodsWe analyzed role of IL-17A in host defense against chronically infected

resultsWe found that TCR γδ

conclusionOur data suggest that the IL-17A-producing TCR γδ

Indexed as

Immunity, CellularAnimalsInterleukin-17LungMaleMiceMice, Inbred C57BLMice, KnockoutReceptors, Antigen, T-Cell, gamma-deltaTuberculosisInterleukin-17Receptors, Antigen, T-Cell, gamma-deltaIL‐17Ainfectious diseaseslung inflammationγδ T cells

Identifiers

PMID27980775
PMCPMC5134718
OpenAlexW2508226116

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.