Evidence map›Paper›PMID 27980530›Full record

ReviewPrzeglad menopauzalny = Menopause review2016

The significance of markers in the diagnosis of endometrial cancer.

Monika M Żyła, Jacek R Wilczyński, Marta Kostrzewa, Kinga Księżakowska-Łakoma, Marek Nowak, Grzegorz Stachowiak, Krzysztof Szyłło, Tomasz Stetkiewicz

Open access · goldAbstract readReview
In one paragraph

Review in Przeglad menopauzalny = Menopause review, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Monika M ŻyłaDepartment of Operative Gynaecology and Gynaecological Oncology, Polish Mother's Memorial Hospital - Research Institute, Łódź, Poland; Chair of Midwifery, Gynaecology and Gynaecological Oncology, Medical University of Łódź, Poland.
Jacek R WilczyńskiDepartment of Operative Gynaecology and Gynaecological Oncology, Polish Mother's Memorial Hospital - Research Institute, Łódź, Poland.
Marta KostrzewaDepartment of Operative Gynaecology and Gynaecological Oncology, Polish Mother's Memorial Hospital - Research Institute, Łódź, Poland.
Kinga Księżakowska-ŁakomaDepartment of Operative Gynaecology and Gynaecological Oncology, Polish Mother's Memorial Hospital - Research Institute, Łódź, Poland.
Marek NowakDepartment of Operative Gynaecology and Gynaecological Oncology, Polish Mother's Memorial Hospital - Research Institute, Łódź, Poland.
Grzegorz StachowiakDepartment of Operative Gynaecology and Gynaecological Oncology, Polish Mother's Memorial Hospital - Research Institute, Łódź, Poland.
Krzysztof SzyłłoDepartment of Operative Gynaecology and Gynaecological Oncology, Polish Mother's Memorial Hospital - Research Institute, Łódź, Poland.
Tomasz StetkiewiczDepartment of Operative Gynaecology and Gynaecological Oncology, Polish Mother's Memorial Hospital - Research Institute, Łódź, Poland.
Polish Mother’s Memorial Hospital Research Institute · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometrial cancer is one of the most common cancers experienced by women throughout the world. It is also the most common malignancy within the female reproductive system, representing 37.7% of all disorders. The incidence increases with age, and is diagnosed most frequently in women between 45 and 65 years old. In the last few years, numerous studies have been performed to identify tumour biomarkers. Biomarkers include not only protein routinely used as tumour markers but also genes and chromosomes. The limiting factor in the use of markers in the diagnosis of endometrial cancer is their lack of specificity. However, specific markers for endometrial cancer are the subject of much research attention. Although moderately elevated levels of markers are present in a number of inflammatory or non-malignant diseases, significantly increased levels of markers indicate the development of cancer. Recently, research has been focused on the identification of molecular changes leading to different histological subtypes of endometrial cancer. In this paper the authors reviewed several currently investigated markers. Progress in these investigations is very important in the diagnostics and treatment of endometrial cancer. In particular, the identification of novel mutations and molecular profiles should enhance our ability to personalise adjuvant treatment with genome-guided targeted therapy.

Indexed as

diagnosticsendometrial cancermarkers

Identifiers

PMID27980530
PMCPMC5137482
OpenAlexW2588587312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.