Evidence map›Paper›PMID 27980399›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2016

Clinical factors and comorbidities affecting the cost of hospital-treated COPD.

Sami Deniz, Aysun Şengül, Yusuf Aydemir, Jülide Çeldir Emre, Mustafa Hikmet Özhan

Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03591250 (Healthcare Renunciation in Patient With Respiratory Chronic Disease and Treatment Compliance), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03591250 completednot on this mapstarted 2018, after this paper: background citation

Healthcare Renunciation in Patient With Respiratory Chronic Disease and Treatment Compliance

TypeobservationalSponsorUniversity Hospital, GrenobleRan2018 to 2022Enrolled1,083ConditionsObstructive Sleep Apnea, Respiratory Failure
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. A Narrative Review of the Correlation Between Comorbidity and Acute Exacerbation of COPD Patients.International journal of chronic obstructive pulmonary disease · 2026
    Review
  5. Observational
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. COPD and Osteoporosis: Associated Factors in Patients Treated with Inhaled Corticosteroids.International journal of chronic obstructive pulmonary disease · 2020
    Article
  18. Trends in Hospitalization Expenditures for Acute Exacerbations of COPD in Beijing from 2009 to 2017.International journal of chronic obstructive pulmonary disease · 2020
    Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Sami DenizClinics of Chest Diseases, Dr Suat Seren Chest Diseases and Thoracic Surgery Education and Research Hospital, İzmir.
Aysun ŞengülClinics of Chest Diseases, Kocaeli Derince Research and Education Hospital, Kocaeli.
Yusuf AydemirDepartment of Chest Diseases, Sakarya University Faculty of Medicine, Sakarya.
Jülide Çeldir EmreClinics of Chest Diseases, Turgutlu State Hospital, Manisa.
Mustafa Hikmet ÖzhanDepartment of Chest Diseases, Faculty of Medicine, Ege University İzmir, Turkey.
Ege University · TRKocaeli Üniversitesi · TRSakarya University · TRState Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to assess the effects of comorbidities on COPD costs and to investigate the relationship between comorbidities and clinical variables. PATIENTS AND

methodsAll patients hospitalized with a diagnosis of COPD exacerbation between January 1, 2014, and December 31, 2014, at all state hospitals of Aydın province, a city located in the western part of Turkey, were included in this study. The costs examined in the study pertained to medications, laboratory tests, hospital stays, and other treatment-related factors, such as consumption of materials, doctor visits, and consultation fees.

resultsA total of 3,095 patients with 5,237 exacerbations (mean age, 71.9±10.5 years; 2,434 males and 661 females) were evaluated. For 880 of the patients (28.9%), or 3,852 of the exacerbations (73.1%), at least one comorbid disease was recorded. The mean cost of each exacerbation was $808.5±1,586, including $325.1±879.9 (40.7%) for hospital stays, $223.1±1,300.9 (27.6%) for medications, $46.3±49.6 (0.9%) for laboratory expenditures, and $214±1,068 (26.5%) for other treatment-related factors, such as consumption of materials, doctor visits, and consultation fees. The cost of each exacerbation was $1,014.9 in patients with at least one comorbidity, whereas it was $233.6 in patients without comorbidity (

conclusionComorbidities have an important role in the total costs of acute exacerbations of COPD. Strategies for the prevention, diagnosis, and effective management of comorbidities would decrease the overall financial burden associated with acute exacerbations of COPD.

Indexed as

Health ExpendituresHospital CostsAgedAged, 80 and overComorbidityDrug CostsFemaleHospitalizationHumansLength of StayMaleMiddle AgedModels, EconomicPulmonary Disease, Chronic ObstructiveReferral and ConsultationRespiratory Function TestscomorbidityCOPDcostexacerbationintensive care unitmorbidity

Identifiers

PMID27980399
PMCPMC5144905
OpenAlexW2559067009

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.