Evidence map›Paper›PMID 27980374›Full record

ReviewJournal of preventive medicine and hygiene2016

History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines.

I Barberis, P Myles, S K Ault, N L Bragazzi, M Martini

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Journal of preventive medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 116 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed, 3 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05521763 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Seasonal Influenza Vaccine Uptake Among Health Care Workers Following Awareness and Availability of Influenza Vaccine Supply in Tertiary Care Hospitals, Bangladesh

TypeinterventionalSponsorInternational Centre for Diarrhoeal Disease Research, BangladeshRan2022 to 2023Enrolled3,000ConditionsInfluenza VaccinesArmsensuring the availability of influenza vaccine supply & developing influenza vaccine awareness
NCT05996549 phase4unknown statusnot on this mapstarted 2022, after this paper: background citation

Acceptability, Cost-Effectiveness, and Capacity of a Facility-Based Seasonal Influenza Vaccination: A Study in Selected Hospitals of Bangladesh

TypeinterventionalSponsorInternational Centre for Diarrhoeal Disease Research, BangladeshRan2022 to 2024Enrolled2,567ConditionsInfluenza Vaccine, Cost-Effectiveness, VaccinationArmsQuadrivalent Influenza Vaccine
3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 3 syntheses or guidelines pooled it, 155 citations in OpenAlex.

  1. Pooled it
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  9. From Yesterday to Tomorrow: How Vaccine Platforms Have Shaped the Vaccine and Treatment Evaluation Units.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
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  15. Observational
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56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

I BarberisDepartment of Health Sciences (DISSAL), University of Genoa, Italy.
P MylesDivision of Epidemiology and Public Health, University of Nottingham, UK.
S K AultPan American Health Organization/World Health Organization (retired), Washington, D.C., United States of America; currently Office of the Dean, School of Public Health, University of Maryland, United States of America.
N L BragazziDepartment of Health Sciences (DISSAL), University of Genoa, Italy.
M MartiniSection of History of Medicine and Ethics, Department of Health Sciences (DISSAL), University of Genoa, Italy.
University of Genoa · ITUniversity of Nottingham · GB

Funding

World Health Organization 001
6 · The paper itself

Abstract

Influenza is a highly infectious airborne disease with an important epidemiological and societal burden; annual epidemics and pandemics have occurred since ancient times, causing tens of millions of deaths. A hundred years after this virus was first isolated, influenza vaccines are an important influenza prevention strategy and the preparations used display good safety and tolerability profiles. Innovative tools, such as recombinant technologies and intra-dermal devices, are currently being investigated in order to improve the immunological response. The recurring mutations of influenza strains has prompted the recent introduction of a quadrivalent inactivated vaccine. In the near future, scientific research will strive to produce a long-lasting universal vaccine containing an antigen that will offer protection against all influenza virus strains.

Indexed as

Influenza VaccinesHumansInfluenza, HumanOrthomyxoviridaeVaccinationInfluenza VaccinesHistory of medicineInfluenzaVaccination

Identifiers

PMID27980374
PMCPMC5139605
OpenAlexW2558489877

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.