Evidence map›Paper›PMID 27980006›Full record

ReviewDiabetes2017

Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis.

Jay S Skyler, George L Bakris, Ezio Bonifacio, Tamara Darsow, Robert H Eckel, Leif Groop, Per-Henrik Groop, Yehuda Handelsman, Richard A Insel, Chantal Mathieu and 7 more

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Diabetes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04444570 (Continuous Glycemia Monitoring in Perioperative Period in Patients Undergoing Total Knee or Hip Arthroplasty), which is not on this map. Cited by 313 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
313citing papers in PubMed, 7 pooled it
36.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04444570 unknown statusnot on this mapstarted 2021, after this paper: background citation

Continuous Glycemia Monitoring in Perioperative Period in Patients Undergoing Total Knee or Hip Arthroplasty: a Protocol of Observational Study

TypeobservationalSponsorMedical University of WarsawRan2021 to 2022Enrolled100ConditionsOsteoarthritis, Knee, Osteoarthritis, Hip, Hyperglycemia, Diabetes Mellitus, Type 2ArmsContinuous glycemia measuring device (Dexcom) implantation into the subcutaneous tissue
3 · Its place in the literature

Who cites it

313 citing papers in PubMed, 7 syntheses or guidelines pooled it, 810 citations in OpenAlex.

  1. Pooled it
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  6. GLP-1a: Going beyond Traditional Use.International journal of molecular sciences · 2022
    Pooled it
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253 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 13 institutions in 7 countries.

Jay S SkylerDiabetes Research Institute, University of Miami Miller School of Medicine, Miami, FL.ORCID 0000-0003-1136-8110
George L BakrisThe University of Chicago Medicine, Chicago, IL.
Ezio BonifacioTechnische Universität Dresden, Dresden, Germany.ORCID 0000-0002-8704-4713
Tamara DarsowAmerican Diabetes Association, Arlington, VA.ORCID 0000-0002-6650-6368
Robert H EckelUniversity of Colorado Anschutz Medical Campus, Aurora, CO.ORCID 0000-0002-4870-4600
Leif GroopLund University, Skåne University Hospital, Malmö, Sweden.ORCID 0000-0002-0187-3263
Per-Henrik GroopAbdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Yehuda HandelsmanMetabolic Institute of America, Tarzana, CA.
Richard A InselJDRF, New York, NY.
Chantal MathieuKatholieke Universiteit Leuven, Leuven, Belgium.
Allison T McElvaineAmerican Diabetes Association, Arlington, VA amcelvaine@diabetes.org.ORCID 0000-0002-0654-4047
Jerry P PalmerUniversity of Washington and VA Puget Sound Health Care System, Seattle, WA.
Alberto PuglieseDiabetes Research Institute, University of Miami Miller School of Medicine, Miami, FL.
Desmond A SchatzUniversity of Florida College of Medicine, Gainesville, FL.ORCID 0000-0002-1044-5762
Jay M SosenkoUniversity of Miami Miller School of Medicine, Miami, FL.
John P H WildingUniversity Hospital Aintree, Liverpool, U.K.ORCID 0000-0003-2839-8404
Robert E RatnerAmerican Diabetes Association, Arlington, VA.
American Diabetes Association · USUniversity of Miami · USBreakthrough T1D · USKU Leuven · BELund University · SETarzana Treatment Centers · USTechnische Universität Dresden · DEUniversity of Chicago · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Florida · USUniversity of Helsinki · FIUniversity of Liverpool · GBUniversity of Washington · US

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1986 to 2026
$41.4M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
TrialNet: University of Florida Clinical Center and NetworkU01DK085461 · NIDDK · UNIVERSITY OF FLORIDA · PI HALLER, MICHAEL JAMES · 2009 to 2018
$5.9M
NIDDK NIH HHS P30 DK017047NIDDK NIH HHS U01 DK085461
6 · The paper itself

Abstract

The American Diabetes Association, JDRF, the European Association for the Study of Diabetes, and the American Association of Clinical Endocrinologists convened a research symposium, "The Differentiation of Diabetes by Pathophysiology, Natural History and Prognosis" on 10-12 October 2015. International experts in genetics, immunology, metabolism, endocrinology, and systems biology discussed genetic and environmental determinants of type 1 and type 2 diabetes risk and progression, as well as complications. The participants debated how to determine appropriate therapeutic approaches based on disease pathophysiology and stage and defined remaining research gaps hindering a personalized medical approach for diabetes to drive the field to address these gaps. The authors recommend a structure for data stratification to define the phenotypes and genotypes of subtypes of diabetes that will facilitate individualized treatment.

Indexed as

Diabetes ComplicationsDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Disease ProgressionGenotypeHumansHypoglycemic AgentsPhenotypePrecision MedicinePrognosisRisk FactorsHypoglycemic Agents

Identifiers

PMID27980006
PMCPMC5384660
OpenAlexW2561206249

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.