Evidence map›Paper›PMID 27979922›Full record

ArticleHaematologica2017

Human RAD52 - a novel player in DNA repair in cancer and immunodeficiency.

Sujal Ghosh, Andrea Hönscheid, Gregor Dückers, Sebastian Ginzel, Holger Gohlke, Michael Gombert, Bettina Kempkes, Wolfram Klapper, Michaela Kuhlen, Hans-Jürgen Laws and 9 more

Open access · goldAbstract readCase ReportsLetter
In one paragraph

Article in Haematologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 2 countries.

Sujal GhoshDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany sujal.ghosh@med.uni-duesseldorf.de.
Andrea HönscheidDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Gregor DückersDepartment of Pediatrics, Helios Hospital Krefeld, Germany.
Sebastian GinzelDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Holger GohlkeInstitute for Pharmaceutical and Medicinal Chemistry, Heinrich-Heine-University, Düsseldorf, Germany.
Michael GombertDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Bettina KempkesDepartment of Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health, Germany.
Wolfram KlapperDepartment of Pathology, Haematopathology Section and Lymph Node Registry, University Medical Centre Schleswig-Holstein, Kiel, Germany.
Michaela KuhlenDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Hans-Jürgen LawsDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
René Martin LinkaDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Roland MeiselDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Christian MielkeInstitute of Clinical Chemistry and Laboratory Diagnostics, Heinrich-Heine-University, Düsseldorf, GermanyMedical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
Tim NiehuesDepartment of Pediatrics, Helios Hospital Krefeld, Germany.
Detlev SchindlerInstitute for Human Genetics, University of Würzburg, Germany.
Dominik SchneiderClinic of Pediatrics, Municipal Hospital Dortmund, Germany.
Friedhelm R SchusterDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Carsten SpeckmannCentre for Chronic Immunodeficiency (CCI) and Centre of Pediatrics, University of Freiburg, Germany.
Arndt BorkhardtDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Heinrich Heine University Düsseldorf · DEHelios Klinikum Krefeld · DEHelmholtz Zentrum München · DEKlinikum Dortmund · DEUniversity College London · GBUniversity Hospital Schleswig-Holstein · DEUniversity of Freiburg · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA RepairAdolescentCell CycleDNA Breaks, Double-StrandedFibroblastsHerpesvirus 4, HumanHumansInfectious MononucleosisMaleMitomycinModels, MolecularProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandRad52 DNA Repair and Recombination ProteinSevere Combined ImmunodeficiencyMitomycinRad52 DNA Repair and Recombination ProteinRAD52 protein, human

Identifiers

PMID27979922
PMCPMC5286958
OpenAlexW2566698199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.