Evidence map›Paper›PMID 27979905›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

A long noncoding RNA, lincRNA-Tnfaip3, acts as a coregulator of NF-κB to modulate inflammatory gene transcription in mouse macrophages.

Shibin Ma, Zhenping Ming, Ai-Yu Gong, Yang Wang, Xiqiang Chen, Guoku Hu, Rui Zhou, Annemarie Shibata, Patrick C Swanson, Xian-Ming Chen

Abstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 78 citations in OpenAlex.

  1. Review
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  6. Fluorescence imaging of MALAT1 expression using a Cy5.5-labeled antisense oligonucleotide in lung cancer and epidermal carcinoma cells.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
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  16. Human Macrophage Long Intergenic Noncoding RNA,Arteriosclerosis, thrombosis, and vascular biology · 2023
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Shibin MaDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA.
Zhenping MingDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA.
Ai-Yu GongDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA.
Yang WangDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA.
Xiqiang ChenDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA.
Guoku HuDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA.
Rui ZhouDepartment of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Hubei, China; and.
Annemarie ShibataDepartment of Biology, College of Arts and Sciences, Creighton University, Omaha, Nebraska, USA.
Patrick C SwansonDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA.
Xian-Ming ChenDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA; xianmingchen@creighton.edu.
Creighton University · USCHI Health Creighton University Medical Center - Bergan Mercy · US

Funding

Molecular Basis of Intestinal CryptosporidiosisR01AI116323 · NIAID · RUSH UNIVERSITY MEDICAL CENTER · PI CHEN, XIAN-MING · 2015 to 2025
$4.2M
Nebraska Center for VirologyP30GM103509 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2012 to 2014
$3.3M
Epithelial exosomes and TLR-mediated mucosal defenseU01AI095532 · NIAID · CREIGHTON UNIVERSITY · PI CHEN, XIAN-MING · 2011 to 2015
$1.5M
Replacing an Animal Resource Facility Cage Washer.G20RR024001 · NCRR · CREIGHTON UNIVERSITY · PI DRESCHER, KRISTEN · 2007 to 2007
$638k
NCRR NIH HHS G20 RR024001NIAID NIH HHS R01 AI116323NIAID NIH HHS U01 AI095532NIGMS NIH HHS P30 GM103509
6 · The paper itself

Abstract

Long intergenic noncoding RNAs (lincRNAs) are long noncoding transcripts (>200 nt) from the intergenic regions of annotated protein-coding genes. We report here that the lincRNA gene

Indexed as

AnimalsCell LineChromatin Assembly and DisassemblyHistonesHMGB1 ProteinMacrophage ActivationMacrophagesMiceNF-kappa BRNA, Long NoncodingTumor Necrosis Factor alpha-Induced Protein 3HistonesHMGB1 ProteinHMGB1 protein, mouseNF-kappa BRNA, Long NoncodingTnfaip3 protein, mouseTumor Necrosis Factor alpha-Induced Protein 3histone modificationsHmgb1inflammationlincRNAs

Identifiers

PMID27979905
PMCPMC6191062
OpenAlexW2561499239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.