ArticleAmerican journal of physiology. Lung cellular and molecular physiology2017
Capsaicin-induced Ca
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Article in American journal of physiology. Lung cellular and molecular physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 50 citations in OpenAlex.
- Next-Generation Metabolic Engineering of Capsaicinoids Biosynthesis in Chilli Pepper: Bridging Genomic Insights to Biotechnological Applications.Biotech (Basel (Switzerland)) · 2026Review
- The Potential Role of Calcium Channels in Pulmonary Hypertension.BioMed research international · 2026Review
- The role of lactate metabolism and lactylation in pulmonary arterial hypertension.Respiratory research · 2025Review
- Role of transient receptor potential channels in the regulation of vascular tone.Drug discovery today · 2024Review
- Up-regulated expression of two-pore domain KFrontiers in cardiovascular medicine · 2024Article
- Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and CaPhysiological reviews · 2023Review
- High oxygen-modified packaging (HiOx-MAP) mediates HIF-1α regulation of tenderness changes during postmortem aging of yak meat.Food chemistry: X · 2023Article
- A journey from molecule to physiology andFrontiers in pharmacology · 2023Review
- TRPC6, a therapeutic target for pulmonary hypertension.American journal of physiology. Lung cellular and molecular physiology · 2021Article
- Zinc-mediated activation of CREB pathway in proliferation of pulmonary artery smooth muscle cells in pulmonary hypertension.Cell communication and signaling : CCS · 2021Article
- Mechanosensitivity in Pulmonary Circulation: Pathophysiological Relevance of Stretch-Activated Channels in Pulmonary Hypertension.Biomolecules · 2021Review
- Transcriptomic profile of cationic channels in human pulmonary arterial hypertension.Scientific reports · 2021Article
- TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes.Scientific reports · 2021Article
- Mechanotransduction in gastrointestinal smooth muscle cells: role of mechanosensitive ion channels.American journal of physiology. Gastrointestinal and liver physiology · 2021Review
- Hydrogen Sulfide-Evoked Intracellular CaCancers · 2020Article
- TRPC and TRPV Channels' Role in Vascular Remodeling and Disease.International journal of molecular sciences · 2020Review
- A Guide to Targeting the Endocannabinoid System in Drug Design.International journal of molecular sciences · 2020Review
- Article
- The potential role of TRPV1 in pulmonary hypertension: Angel or demon?Channels (Austin, Tex.) · 2019Review
- TRPPing up bronchiectasis.American journal of physiology. Lung cellular and molecular physiology · 2019Article
Corrections and comments
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Authors and funding
17 authors at 3 institutions in 2 countries.
Shanshan SongDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Ramon J AyonDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Aya YamamuraKinjo Gakuin University School of Pharmacy, Nagoya, Japan; and.
Hisao YamamuraNagoya City University Graduate School of Pharmaceutical Sciences, Nagoya, Japan.
Swetaleena DashDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Aleksandra BabichevaDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Haiyang TangDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Xutong SunDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Arlette G CorderyDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Zain KhalpeyDepartment of Surgery, The University of Arizona College of Medicine, Tucson, Arizona.
Stephen M BlackDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Ankit A DesaiDepartment of Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Franz RischardDepartment of Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Kimberly M McDermottDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Joe G N GarciaDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Ayako MakinoDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.
Jason X-J YuanDivision of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona; jasonyuan@email.arizona.edu.
University of Arizona · USKinjo Gakuin University · JPNagoya City University · JP
Funding
Therapeutic Mechanisms of RhoA Inhibition In Acute Lung InjuryP01HL101902 · NHLBI · AUGUSTA UNIVERSITY · PI BLACK, STEPHEN M · 2011 to 2016
$11.2MPERINATAL REGULATION OF THE ENDOTHELIAL NOS GENER01HL060190 · NHLBI · UNIVERSITY OF MONTANA · PI Stephen M Black · 1998 to 2026
$7.1MIon Channels and Membrane Receptors in Pulmonary Arterial HypertensionR35HL135807 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI YUAN, JASON X J · 2017 to 2023
$5.6MCapacitative Ca2+ Entry in Pulmonary Myocyte GrowthR01HL066012 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YUAN, JASON X J · 2002 to 2016
$5.2MROS in Pulmonary Hypertension: Role of ADMAR01HL067841 · NHLBI · UNIVERSITY OF MONTANA · PI BLACK, STEPHEN M · 2002 to 2011
$2.6MPathogenic Role of IL-18 in Sickle Cell Cardiomyopathy and Inducible Ventricular TachycardiaR01HL136603 · NHLBI · UNIVERSITY OF ARIZONA · PI DESAI, ANKIT A · 2017 to 2021
$2.4MMolecular mechanisms of downregulated Kv channels in IPAH: Role of microRNAR01HL115014 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YUAN, JASON X J · 2012 to 2016
$2.2MPhenomic and genomic study to subphenotype Hispanics with pulmonary hypertensionU01HL125208 · NHLBI · UNIVERSITY OF ARIZONA · PI GARCIA, JOE G. N., RISCHARD, FRANZ P · 2014 to 2018
$1.5MNHLBI NIH HHS P01 HL101902NHLBI NIH HHS R01 HL060190NHLBI NIH HHS R01 HL066012NHLBI NIH HHS R01 HL067841NHLBI NIH HHS R01 HL115014NHLBI NIH HHS R01 HL136603NHLBI NIH HHS R35 HL135807NHLBI NIH HHS U01 HL125208
Abstract
Capsaicin is an active component of chili pepper and a pain relief drug. Capsaicin can activate transient receptor potential vanilloid 1 (TRPV1) channels to increase cytosolic Ca
Indexed as
AdultCalcium SignalingCapsaicinCell ProliferationChloride ChannelsCyclic AMP Response Element-Binding ProteinDiterpenesElectric ConductivityExtracellular SpaceFamilial Primary Pulmonary HypertensionFemaleGene Knockdown TechniquesHumansHydrogen-Ion ConcentrationMaleMiddle AgedCapsaicincapsazepineChloride ChannelsCyclic AMP Response Element-Binding ProteinDiterpenesiodoresiniferatoxinPotassium ChannelsTRPV1 protein, humanTRPV Cation Channelscapsaicinidiopathic pulmonary arterial hypertensionmechanosensitive cation channelsosmotic pressureTRPV1
Identifiers
What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.