Evidence map›Paper›PMID 27979046›Full record

Trial reportAmerican heart journal2017

Effects of exercise and stress management training on nighttime blood pressure dipping in patients with coronary heart disease: A randomized, controlled trial.

Andrew Sherwood, Patrick J Smith, Alan L Hinderliter, Anastasia Georgiades, James A Blumenthal

Open access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in American heart journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Andrew SherwoodDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC. Electronic address: sherw002@mc.duke.edu.
Patrick J SmithDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC.
Alan L HinderliterDepartment of Medicine, University of North Carolina, Chapel Hill, NC.
Anastasia GeorgiadesDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC.
James A BlumenthalDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC.
Duke Medical Center · USDuke University Hospital · USUniversity of North Carolina at Chapel Hill · US

Funding

STRESS AND MYOCARDIAL ISCHEMIA--MECHANISMS AND TREATMENTR01HL059672 · NHLBI · DUKE UNIVERSITY · PI BLUMENTHAL, JAMES A. · 1998 to 2002
$2.5M
NHLBI NIH HHS R01 HL059672
6 · The paper itself

Abstract

introductionBlunted nighttime blood pressure (BP) dipping is prognostic of cardiovascular morbidity and mortality. Patients with coronary heart disease (CHD) are often characterized by a blunted nighttime BP dipping pattern. The present study compared the effects of 2 behavioral intervention programs, aerobic exercise (EX) and stress management (SM) training, with a usual care (UC) control group on BP dipping in a sample of CHD patients.

methodsThis was a secondary analysis of a randomized, controlled trial with allocation concealment and blinded outcome assessment in 134 patients with stable CHD and exercise-induced myocardial ischemia. Nighttime BP dipping was assessed by 24-hour ambulatory BP monitoring, at prerandomization baseline and after 16 weeks of one of the following treatments: usual medical care; UC plus supervised aerobic EX for 35 minutes, 3 times per week; UC plus weekly 1.5-hour sessions of SM training.

resultsThe EX and SM groups exhibited greater improvements in systolic BP dipping (P=.052) and diastolic BP dipping (P=.031) compared with UC. Postintervention systolic BP percent-dipping means were 12.9% (SE=1.5) for SM, 11.1% (SE=1.4) for EX, and 8.6% (SE=1.4) for UC. Postintervention diastolic BP percent-dipping means were 13.3% (SE=1.9) for SM, 14.1% (SE=1.8) for EX, and 8.8% (1.8) for UC.

conclusionsFor patients with stable CHD, EX or SM training resulted in improved nighttime BP dipping compared with usual medical care. These favorable effects of healthy lifestyle modifications may help reduce the risk of adverse clinical events.

Indexed as

Blood PressureCircadian RhythmCoronary DiseaseExerciseFemaleHumansMaleMiddle AgedSingle-Blind MethodStress, Psychological

Identifiers

PMID27979046
PMCPMC5172393
OpenAlexW2535586463

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.