ArticlePloS one2016
Risk Factors for the Rupture of Middle Cerebral Artery Bifurcation Aneurysms Using CT Angiography.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Baseline demographic and aneurysm morphologic features associated with woven endobridge angiographic outcomes: A systematic review and meta-analysis.Neuroradiology · 2025Pooled it
- Morphology and variations of middle cerebral artery: systematic review and meta-analysis.Anatomy & cell biology · 2024Review
- Textbook Outcomes Among Patients with Aneurysmal Subarachnoid Hemorrhage Following Endovascular Treatment.Neurology and therapy · 2024Article
- Morphological Characteristics of Ruptured Brain Aneurysms: A Systematic Literature Review and Meta-Analysis.Stroke (Hoboken, N.J.) · 2023Article
- A web-based dynamic nomogram for rupture risk of posterior communicating artery aneurysms utilizing clinical, morphological, and hemodynamic characteristics.Frontiers in neurology · 2022Article
- Asymmetry of P1 and vertebral arteries is not related to basilar tip aneurysm development or rupture.Acta neurochirurgica · 2021Article
- Morphological variables associated with ruptured basilar tip aneurysms.Scientific reports · 2021Article
- Risk Factors for Intraprocedural Rerupture during Embolization of Ruptured Intracranial Aneurysms.Journal of Korean medical science · 2020Article
- Age and morphology of posterior communicating artery aneurysms.Scientific reports · 2020Article
- Anatomical evaluation of intracranial aneurysm rupture risk in patients with multiple aneurysms.Neurosurgical review · 2019Article
- Associations of hemodynamics, morphology, and patient characteristics with aneurysm rupture stratified by aneurysm location.Neuroradiology · 2019Article
- A Simple Scoring Model for Prediction of Rupture Risk of Anterior Communicating Artery Aneurysms.Frontiers in neurology · 2019Article
- Development of a statistical model for discrimination of rupture status in posterior communicating artery aneurysms.Acta neurochirurgica · 2018Article
- Wall enhancement ratio and partial wall enhancement on MRI associated with the rupture of intracranial aneurysms.Journal of neurointerventional surgery · 2018Article
- Risk factors for ruptured intracranial aneurysms.The Indian journal of medical research · 2018Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
background and purposeTo investigate the clinical and morphological characteristics associated with risk factors for the rupture of bifurcation-type middle cerebral artery aneurysms (MCAAs).
methodsA total of 169 consecutive patients with 177 bifurcation-type MCAAs were reviewed from August 2011 to January 2016. Based on the clinical and morphologic characteristics findings, the risk factors of aneurysm rupture were assessed using statistical methods.
resultsAge, cerebral atherosclerosis, no hypertension, hypertension grade 2 and coronary artery disease (CAD) were negatively correlated with aneurysm rupture. The mean diameter (MD) of the parent and two daughter arteries was negatively correlated with rupture. Aneurysms with irregularity, depth, width, maximum size, aspect ratio, depth-to-width ratio, bottleneck factor, and size ratio were positively correlated with rupture. The multivariate logistic regression model revealed that irregular shape (odds ratio (OR) 2.697) and aspect ratio (OR 3.723) were significantly and positively correlated with rupture, while cerebral atherosclerosis (OR 0.033), CAD (OR 0.080), and MD (OR 0.201) were negatively correlated with rupture. Receiver operating characteristic analysis revealed that the threshold value of the aspect ratio and MD were 0.96 and 2.43 mm, respectively.
conclusionsCerebral atherosclerosis and CAD are protective factors against rupture. Morphological characteristics such as an aneurysm with an irregular shape, a high aspect ratio (>0.96) and a small MD (<2.43 mm) are likely better predictors of rupture.
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