ArticlePLoS genetics2016
NUCLEAR FACTOR Y, Subunit A (NF-YA) Proteins Positively Regulate Flowering and Act Through FLOWERING LOCUS T.
Article in PLoS genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed.
- Genome-Wide Identification of the ZmNF-Y Transcription Factor Family in Maize and Functional Characterization of ZmNF-YA7 in Drought Tolerance.International journal of molecular sciences · 2026Article
- Genetic mechanisms for size- and light-dependent reproductive maturation in two maple species, Acer amoenum var. amoenum and Acer mono var. glabrum.Annals of botany · 2026Article
- Haplotype-resolved genome assembly of a male Dioscorea alata cultivar reveals the structure and evolution of young sex chromosomes.The Plant journal : for cell and molecular biology · 2026Article
- NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Introgressed Variation in TaMYB7-A1 Drives Graded Dormancy and Climate-Adaptive Pre-Harvest Sprouting Resistance in Wheat.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Synthetic promoter design in plants: integration of computational and experimental approaches.Frontiers in plant science · 2026Review
- Identification of circRNAs in industrial hemp (Frontiers in plant science · 2026Article
- Genome-wide identification and analysis of the NF-Y transcription factor family reveal its potential roles in tobacco (Plant signaling & behavior · 2025Article
- Multi-omics integration of transcriptome, miRNA, and metabolome uncovers molecular mechanisms of male flower development in cucumber line B10 (Cucumis sativus L.).Scientific reports · 2025Article
- Nuclear factor-Y transcription factors in crops: Biological roles, regulation, and breeding applications.Plant communications · 2025Review
- The bZIP3-AS1 complex promotes CONSTANS-induced FLOWERING LOCUS T activation in a daylength-dependent manner.Journal of integrative plant biology · 2025Article
- An Introduction to Network Analysis in Plant Biology.Plant direct · 2025Article
- Abscisic acid and GIGANTEA signalling converge to regulate the recruitment of CONSTANS to the FT promoter and activate floral transition.Journal of experimental botany · 2025Article
- Natural allelic variation in SW14 determines seed weight and quality in soybean.Nature communications · 2025Article
- Delay in Flowering Time inInternational journal of molecular sciences · 2025Article
- Characterization of FLOWERING LOCUS T-related genes and their putative gene regulatory network in semi-winter Brassica napus cultivar Zhongshaung11.The Plant journal : for cell and molecular biology · 2025Article
- Integrated expression analysis to elucidate the role of miR394 during flowering in Arabidopsis thaliana.Plant cell reports · 2025Article
- Durum wheat nuclear factor Y (NF-Y) a subfamily: structure, phylogeny, and expression analysis in response to hormones and abiotic stresses.Functional & integrative genomics · 2025Article
- Plant Nuclear Factor Y (NF-Y) Transcription Factors: Evolving Insights into Biological Functions and Gene Expansion.International journal of molecular sciences · 2024Review
- Nuclear factor-Y-polycomb repressive complex2 dynamically orchestrates starch and seed storage protein biosynthesis in wheat.The Plant cell · 2024Article
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Authors and funding
7 authors.
Funding
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Abstract
Photoperiod dependent flowering is one of several mechanisms used by plants to initiate the developmental transition from vegetative growth to reproductive growth. The NUCLEAR FACTOR Y (NF-Y) transcription factors are heterotrimeric complexes composed of NF-YA and histone-fold domain (HFD) containing NF-YB/NF-YC, that initiate photoperiod-dependent flowering by cooperatively interacting with CONSTANS (CO) to drive the expression of FLOWERING LOCUS T (FT). This involves NF-Y and CO binding at distal CCAAT and proximal "CORE" elements, respectively, in the FT promoter. While this is well established for the HFD subunits, there remains some question over the potential role of NF-YA as either positive or negative regulators of this process. Here we provide strong support, in the form of genetic and biochemical analyses, that NF-YA, in complex with NF-YB/NF-YC proteins, can directly bind the distal CCAAT box in the FT promoter and are positive regulators of flowering in an FT-dependent manner.
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