SynthesisMedicine2016
A meta-analytic review of prevalence for Brugada ECG patterns and the risk for death.
Synthesis in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04641585 (Brugada Syndrome and Artificial Intelligence Applications to Diagnosis), which is not on this map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Brugada Syndrome and Artificial Intelligence Applications to Diagnosis
Who cites it
27 citing papers in PubMed.
- Beyond Common Arrhythmias: Discovering Brugada Syndrome in a Patient With Nonspecific Symptoms.Cureus · 2026Article
- Case Report: Brugada syndrome uncovered by delivery in a 32-year-old patient.Frontiers in cardiovascular medicine · 2026Article
- Brugada syndrome.Nature reviews. Disease primers · 2025Review
- 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2025Review
- External validation and comparative performance of the SLANT score for neuroprognostication in out-of-hospital cardiac arrest survivors undergoing targeted temperature management: insights from an Asian cohort.Journal of intensive care · 2025Article
- Prevalence and associated factors of ECG abnormality patterns indicative of cardiac channelopathies among adult general population of Tehran, Iran: a report from the Tehran Cohort Study (TeCS).BMC cardiovascular disorders · 2024Article
- Ion Channel Diseases as a Cause of Sudden Cardiac Death in Young People: Aspects of Their Diagnosis, Treatment, and Pathogenesis.Deutsches Arzteblatt international · 2024Review
- 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2024Review
- Echo state networks for the recognition of type 1 Brugada syndrome from conventional 12-LEAD ECG.Heliyon · 2024Article
- GPD1L-A306del modifies sodium current in a family carrying the dysfunctional SCN5A-G1661R mutation associated with Brugada syndrome.Pflugers Archiv : European journal of physiology · 2024Article
- Challenges in Brugada Syndrome Stratification: InvestigatingInternational journal of molecular sciences · 2023Article
- Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association.Circulation · 2023Review
- Alterations of the Sialylation Machinery in Brugada Syndrome.International journal of molecular sciences · 2022Article
- Concealed Substrates in Brugada Syndrome: Isolated Channelopathy or Associated Cardiomyopathy?Genes · 2022Review
- Brugada Syndrome: Different Experimental Models and the Role of Human Cardiomyocytes From Induced Pluripotent Stem Cells.Journal of the American Heart Association · 2022Review
- Brugada Syndrome: When Strict Treatment of Febrile Episodes Really Matters.Journal of community hospital internal medicine perspectives · 2022Article
- Brugada syndrome: should we be screening patients before prescribing psychotropic medication?Therapeutic advances in psychopharmacology · 2022Review
- The BrAID study protocol: integration of machine learning and transcriptomics for brugada syndrome recognition.BMC cardiovascular disorders · 2021Article
- Brugada ECG Pattern - A Blip on the Radar for a Pontentially Life-Threatening Condition.Arquivos brasileiros de cardiologia · 2021Article
- Telemedicine for detecting Brugada Syndrome in eastern Indonesia: A multi-center prospective observational study.Annals of medicine and surgery (2012) · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of Brugada ECG pattern (BrEP) is different in different regions, and its mean prevalence over the world is unknown. The risk of people with BrEP for death remains unknown. We performed a meta-analysis to determine the prevalence of BrEP and risk ratio (RR) for death.
methodsRelevant studies published between July 1, 2000 and August 20, 2016, which contain prevalence and RR for all-cause death and cardiac death, were included. The prevalence and RR are analyzed using meta-analysis.
resultsWe finally retrieved 24 studies of the prevalence for BrEP and 5 studies of the RR for all-cause death and cardiac death. The worldwide mean prevalence of BrEP is 0.4%, with highest in Asia (0.9%) and lowest in North America (0.2%). Additionally, the mean prevalence in male is 0.9%, whereas it is 0.1% in female. The RR of BrEP for all-cause death is 0.78 (95% confidence interval 0.45-1.37), and for cardiac death it is 0.92 (95% confidence interval 0.23-3.66).
conclusionThe prevalence of BrEP is about 0.4% around the world with different prevalence in region and sex. Our study shows that BrEP may not be taken as a predictor of all-cause death and cardiac death.
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