Observational studyPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2017
Delirium in Children After Cardiac Bypass Surgery.
Observational study in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03572257 (Prospective, Double-Blind, Randomized Controlled Trial of Quetiapine as a Treatment for Delirium in Critically Ill Children), which is not on this map. Cited by 57 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective, Double-Blind, Randomized Controlled Trial of Quetiapine as a Treatment for Delirium in Critically Ill Children
Who cites it
57 citing papers in PubMed, 6 syntheses or guidelines pooled it, 161 citations in OpenAlex.
- Impact of Delirium on Pediatric Critical Care Outcomes and Management Strategies: A Systematic Review and Meta-Analysis.Journal of nursing management · 2026Pooled it
- Prevalence of pediatric delirium among critically ill children: a meta-analysis of observational studies.Frontiers in pediatrics · 2026Pooled it
- Risk factors and incidence of postoperative delirium after cardiac surgery in children: a systematic review and meta-analysis.Italian journal of pediatrics · 2024Pooled it
- Efficacy and safety of perioperative application of ketamine on postoperative depression: A meta-analysis of randomized controlled studies.Molecular psychiatry · 2023Pooled it
- Pooled it
- State of the science in pediatric ICU delirium: An integrative review.Research in nursing & health · 2020Pooled it
- Feature Analysis for Evaluating the Risk of Postoperative Delirium in Pediatric Patients.Journal of clinical medicine · 2026Article
- Effect of Neurologic Conditions on Delirium Duration and Time to ICU Discharge.Critical care explorations · 2026Observational
- Longitudinal patterns of postoperative brain oxygen saturation in children with congenital heart disease and postoperative delirium risk: a repeated measures analysis.Frontiers in pediatrics · 2026Article
- Incidence and risk factors of postoperative delirium in children with congenital heart disease.PloS one · 2026Article
- Article
- Non-pharmacological interventions for delirium in critically ill children: a scoping review.BMJ open · 2025Article
- Prevalence and Risk Factors of Pediatric Delirium in Critically Ill Children: A Study Using Cornell Assessment of Pediatric Delirium Tool at a Tertiary Care Hospital.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- Incidence of pediatric delirium and withdrawal outside the PICU: findings from a pediatric cardiology ward.European journal of pediatrics · 2025Observational
- Prevalence of and risk factors for postoperative delirium among children after cardiac surgery in a Single-Centre retrospective study.Scientific reports · 2025Article
- The Effect of Impaired Cerebral Autoregulation on Postoperative Delirium in Neonates and Infants After Corrective Cardiac Surgery: A Study on Modifiable Risk Factors for Delirium.Reviews in cardiovascular medicine · 2025Article
- Mental Health Care for Children with Heart Disease and Their Families: Practical Approaches and Considerations for the Pediatric and Pediatric Cardiology Clinician.Pediatric cardiology · 2025Review
- Clinical Benefits and Challenges of Esketamine in Elderly Patients During the Perioperative Period.Drug design, development and therapy · 2025Review
- Risk Factors of Prolonged Mechanical Ventilation in Post Coronary Artery Bypass Graft Patients: A Scoping Review.Journal of multidisciplinary healthcare · 2025Review
- Age-specific vulnerability and high prevalence of delirium in pediatric intensive care based on a prospective cohort study.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesTo describe the incidence of delirium in pediatric patients after cardiac bypass surgery and explore associated risk factors and effect of delirium on in-hospital outcomes.
designProspective observational single-center study.
settingFourteen-bed pediatric cardiothoracic ICU. PATIENTS: One hundred ninety-four consecutive admissions following cardiac bypass surgery, 1 day to 21 years old.
interventionsSubjects were screened for delirium daily using the Cornell Assessment of Pediatric Delirium. MEASUREMENTS AND MAIN
resultsIncidence of delirium in this sample was 49%. Delirium most often lasted 1-2 days and developed within the first 1-3 days after surgery. Age less than 2 years, developmental delay, higher Risk Adjustment for Congenital Heart Surgery 1 score, cyanotic disease, and albumin less than three were all independently associated with development of delirium in a multivariable model (all p < 0.03). Delirium was an independent predictor of prolonged ICU length of stay, with patients who were ever delirious having a 60% increase in ICU days compared with patients who were never delirious (p < 0.01).
conclusionsIn our institution, delirium is a frequent problem in children after cardiac bypass surgery, with identifiable risk factors. Our study suggests that cardiac bypass surgery significantly increases children's susceptibility to delirium. This highlights the need for heightened, targeted delirium screening in all pediatric cardiothoracic ICUs to potentially improve outcomes in this vulnerable patient population.
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