Evidence map›Paper›PMID 27977503›Full record

ArticlePsychosomatic medicine2017

Chronic Stress and C-Reactive Protein in Mothers During the First Postpartum Year.

Christine M Guardino, Christine Dunkel Schetter, Calvin J Hobel, Robin Gaines Lanzi, Peter Schafer, John M Thorp, Madeleine U Shalowitz, Community Child Health Network (CCHN)

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Psychosomatic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Chronic stress and hair cortisol concentration in mothers: A two-study investigation.Stress and health : journal of the International Society for the Investigation of Stress · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Subjective social status and allostatic load in mothers 1 year after birth.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022
    Article
  9. Article
  10. Utilizing Datasets to Advance Perinatal Research.Journal of midwifery & women's health · 2017
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 3 countries.

Christine M GuardinoFrom the Department of Psychology (Guardino, Dunkel Schetter), University of California, Los Angeles; Department of Obstetrics and Gynecology (Hobel), Division of Maternal-Fetal Medicine, The Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, California; Department of Health Behavior (Lanzi), University of Alabama at Birmingham; Health Policy (Schafer), New York Academy of Medicine; Obstetrics and Gynecology (Thorp), University of North Carolina, Chapel Hill; North Shore University Health System Research Institute and Department of Pediatrics (Shalowitz), University of Chicago, Illinois; and Eunice Kennedy Shriver National Institute of Child Health and Human Development (CHNN).
Christine Dunkel Schetter
Calvin J Hobel
Robin Gaines Lanzi
Peter Schafer
John M Thorp
Madeleine U Shalowitz
Community Child Health Network (CCHN)
Angeles University Foundation · PH

Funding

Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Community Child Health Network-Lake County, ILU01HD044226 · NICHD · NORTHSHORE UNIV HEALTHSYSTEM RES INST · PI SHALOWITZ, MADELEINE ULLMAN · 2003 to 2011
$3.9M
Community Response to Maternal/Child Health DisparitiesU01HD044245 · NICHD · CEDARS-SINAI MEDICAL CENTER · PI HOBEL, CALVIN J. · 2003 to 2011
$3.4M
Community Child Health Network: District of ColumbiaU01HD044253 · NICHD · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI RAMEY, SHARON LANDESMAN · 2007 to 2011
$3.3M
Community Child Health Network: BaltimoreU01HD044207 · NICHD · ST. MICHAEL'S HOSPITAL · PI VANCE, MAXINE · 2003 to 2012
$3.2M
Community Maternal &Child Health-Eastern North CarolinaU01HD044219 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI THORP, JOHN M · 2003 to 2011
$3.1M
Data Coordination and Analyses Center for the Community and Child Health NetworkU01HD054791 · NICHD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI CHINCHILLI, VERNON M · 2006 to 2011
$2.7M
Community Child Health Research in Washington, D.C.U01NR008929 · NINR · GEORGETOWN UNIVERSITY · PI RAMEY, SHARON LANDESMAN · 2003 to 2006
$630k
Documenting the CAPPR Process in the L.A. Site of the Community Child Health NetwR03HD059584 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WRIGHT, KYNNA N · 2008 to 2009
$138k
PEDIATRIC EPIDEMIOLOGY OF CVD RISK FACTORSU01HL041166 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LABARTHE, DARWIN R. · 1990 to 1995
–
NHLBI NIH HHS U01 HL041166NICHD NIH HHS P2C HD050924NICHD NIH HHS R03 HD059584NICHD NIH HHS U01 HD044207NICHD NIH HHS U01 HD044219NICHD NIH HHS U01 HD044226NICHD NIH HHS U01 HD044245NICHD NIH HHS U01 HD044253NICHD NIH HHS U01 HD054791NINR NIH HHS U01 NR008929
6 · The paper itself

Abstract

objectiveElevated levels of C-reactive protein (CRP) are associated with increased risk of cardiovascular and metabolic disease. The current study tested associations between psychosocial stress and CRP in a large sample of women during the first postpartum year.

methodsWe analyzed data collected by the five-site Community Child Health Network study, which studied a predominately poor population. Participants (n = 1206 women; 54% African American, 23% white, 23% Hispanic/Latina) were recruited shortly after the birth of a child. Multiple linear regression analyses tested associations of psychosocial stress in several life domains (financial, neighborhood, family, coparenting, partner relationship, discrimination, and interpersonal violence) with log-transformed CRP concentrations at 6-month and 1-year postpartum.

resultsForty-eight percent of participants showed evidence of elevated CRP (≥3 mg/L) at 6-month postpartum, and 46% had elevated CRP at 12-month postpartum. Chronic financial stress at 1-month postpartum predicted higher levels of CRP at 6- (b = .15, SE = .05, p = .006) and 12-month postpartum (b = .15, SE = .06, p = .007) adjusting for race/ethnicity, income, education, parity, health behaviors, and chronic health conditions, though associations became nonsignificant when adjusted for body mass index.

conclusionsIn this low-income and ethnic/racially diverse sample of women, higher financial stress at 1-month postbirth predicted higher CRP. Study findings suggest that perceived financial stress stemming from socioeconomic disadvantage may be a particular deleterious form of stress affecting maternal biology during the year after the birth of a child.

Indexed as

AdolescentAdultBody Mass IndexC-Reactive ProteinFemaleHumansLongitudinal StudiesPostpartum PeriodSocioeconomic FactorsStress, PsychologicalYoung AdultC-Reactive Protein

Identifiers

PMID27977503
PMCPMC6619505
OpenAlexW2563384129

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.