Evidence map›Paper›PMID 27977330›Full record

ArticleCell cycle (Georgetown, Tex.)2017

Hmga1 deficiency: "SAC-King" the SAC genes to incite chromosomal instability.

Lingling Xian, Karen A Reddy, Linda M S Resar

Abstract readComment
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The role of HMGA1 in genome stability: Implications in human cancer.Cellular and molecular life sciences : CMLS · 2026
    Review
  2. EZH2-CCF-cGAS Axis Promotes Breast Cancer Metastasis.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Lingling Xiana Department of Medicine , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Karen A Reddya Department of Medicine , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Linda M S Resara Department of Medicine , Johns Hopkins University School of Medicine , Baltimore , MD , USA.

Funding

Prevention of COX-2 Derived DNA and Histone Modifications in CancerR21CA187495 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OATES, JOHN ALEXANDER · 2015 to 2016
$394k
Developing a Screen for Novel Therapies with Reprogrammed Pancreatic Cancer CellsR03CA191621 · NCI · JOHNS HOPKINS UNIVERSITY · PI RESAR, LINDA M S · 2015 to 2016
$162k
Developing Nanotechnology to Target HMGA1 in Pancreatic CancerR03CA182679 · NCI · JOHNS HOPKINS UNIVERSITY · PI RESAR, LINDA M S · 2014 to 2015
$151k
NCI NIH HHS R03 CA182679NCI NIH HHS R03 CA191621NCI NIH HHS R21 CA187495
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chromosomal InstabilityM Phase Cell Cycle CheckpointsHumanschromosomal instabilityCINhigh mobility group A1HMGA1SACspindle associated checkpoint

Identifiers

PMID27977330
PMCPMC5270530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.