ArticleGenetics in medicine : official journal of the American College of Medical Genetics2017
Public variant databases: liability?
Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Early considerations for village-in-a-dish platform: a multidisciplinary perspective.Frontiers in bioengineering and biotechnology · 2026Review
- Article
- Microbial Genomics as a Catalyst for Targeted Antivirulence Therapeutics.Frontiers in medicine · 2021Article
- The case for implementing sustainable routine, population-level genomic reanalysis.Genetics in medicine : official journal of the American College of Medical Genetics · 2020Article
- A catalogue of new incidence estimates of monogenic neurodevelopmental disorders caused by de novo variants.Brain : a journal of neurology · 2020Article
- From Genetics to Genomics: Facing the Liability Implications in Clinical Care.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2020Article
- Human gene and disease associations for clinical-genomics and precision medicine research.Clinical and translational medicine · 2020Article
- Pharmacogenomic Testing: Clinical Evidence and Implementation Challenges.Journal of personalized medicine · 2019Review
- Variant data sharing by clinical laboratories through public databases: consent, privacy and further contact for research policies.Genetics in medicine : official journal of the American College of Medical Genetics · 2019Article
- Genomic Testing for Human Health and Disease Across the Life Cycle: Applications and Ethical, Legal, and Social Challenges.Frontiers in public health · 2019Review
- Legal challenges for the implementation of advanced clinical digital decision support systems in Europe.Journal of clinical and translational research · 2018Article
- BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2.PLoS genetics · 2018Article
- Analysis of VUS reporting, variant reinterpretation and recontact policies in clinical genomic sequencing consent forms.European journal of human genetics : EJHG · 2018Article
- Genetic database software as medical devices.Human mutation · 2018Article
- Observed frequency and challenges of variant reclassification in a hereditary cancer clinic.Genetics in medicine : official journal of the American College of Medical Genetics · 2018Article
- Physicians' duty to recontact and update genetic advice.Personalized medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Public variant databases support the curation, clinical interpretation, and sharing of genomic data, thus reducing harmful errors or delays in diagnosis. As variant databases are increasingly relied on in the clinical context, there is concern that negligent variant interpretation will harm patients and attract liability. This article explores the evolving legal duties of laboratories, public variant databases, and physicians in clinical genomics and recommends a governance framework for databases to promote responsible data sharing.Genet Med advance online publication 15 December 2016.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.