Evidence map›Paper›PMID 27976643›Full record

ArticleSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association2016

Gluten-Free hepatomiracle in "celiac hepatitis": A case highlighting the rare occurrence of nutrition-induced near total reversal of advanced steatohepatitis and cirrhosis.

Kavita Gaur, Puja Sakhuja, Amarender S Puri, Kaushik Majumdar

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. MAFLD and Celiac Disease in Children.International journal of molecular sciences · 2023
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kavita GaurDepartment of Pathology, GB Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India.
Puja SakhujaDepartment of Pathology, GB Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India.
Amarender S PuriDepartment of Gastroenterology, GB Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India.
Kaushik MajumdarDepartment of Pathology, GB Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India.
Institute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regression of hepatic fibrosis is increasingly becoming a reality, both in clinical as well as experimental models. Reversal or near-total regression of marked liver steatohepatitis and fibrosis, however, remains a rare event. We report the case of a 20-year-old female presenting with diarrhea due to celiac disease and biopsy proven cirrhosis with portal hypertension who had a remarkable clinical improvement in response to a gluten free diet (GFD). A follow-up liver biopsy 9 months after the initiation of GFD revealed a remarkable regression of both fibrosis as well as steatosis. Villous atrophy, as seen in patients with celiac disease, could lead to a deprivation of trophic factors leading to liver injury and subsequent cirrhosis. A gluten-free dietary regimen can produce a reversal of fibrosis leading to the amelioration of symptoms associated even with advanced liver disease.

Indexed as

AftercareCeliac DiseaseDiarrheaDiet, Gluten-FreeFatty LiverFemaleHumansIntestinal MucosaLiverLiver CirrhosisTreatment OutcomeYoung Adult

Identifiers

PMID27976643
PMCPMC5184748
OpenAlexW2562660658

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.