Evidence map›Paper›PMID 27976536›Full record

ArticleAdvanced healthcare materials2017

A Facile and Versatile Method to Endow Biomaterial Devices with Zwitterionic Surface Coatings.

Volkan Yesilyurt, Omid Veiseh, Joshua C Doloff, Jie Li, Suman Bose, Xi Xie, Andrew R Bader, Michael Chen, Matthew J Webber, Arturo J Vegas and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Advanced healthcare materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Drug delivery carriers with therapeutic functions.Advanced drug delivery reviews · 2021
    Review
  11. Article
  12. Article
  13. Review
  14. Vapor-Deposited Biointerfaces and Bacteria: An Evolving Conversation.ACS biomaterials science & engineering · 2020
    Review
  15. Review
  16. Review
  17. Review
  18. Engineering Precision Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019
    Review
  19. Article
  20. Fibrinogen adsorption to biomaterials.Journal of biomedical materials research. Part A · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Volkan YesilyurtDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Omid VeisehDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Joshua C DoloffDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Jie LiDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Suman BoseDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Xi XieDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Andrew R BaderDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Michael ChenDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Matthew J WebberDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Arturo J VegasDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Robert LangerDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Daniel G AndersonDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Boston Children's Hospital · USMassachusetts Institute of Technology · USBoston University · US

Funding

VIRUS PRODUCTION COREP30CA014051 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI MATTHEW G. VANDER HEIDEN · 1985 to 2026
$93.9M
Stochastic gene expression in differentiation and developmentDP1CA174420 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI VAN OUDENAARDEN, ALEXANDER · 2012 to 2012
$832k
Array development of anti-inflammatory peptoid-graft polymers for islet deliveryF32DK101335 · NIDDK · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI WEBBER, MATTHEW · 2013 to 2015
$159k
NCI NIH HHS DP1 CA174420NCI NIH HHS P30 CA014051NIDDK NIH HHS F32 DK101335
6 · The paper itself

Abstract

The surface modification of implantable biomaterials with zwitterionic phosphorylcholine polymer is demonstrated through mussel-mimetic catecholamine polymer thin films. Using this method, the surfaces of alginate hydrogel microspheres and polystyrene microbeads, a model material known to produce robust foreign body responses and fibrosis, are successfully modified to reduce the tissue reaction by reducing the fibrosis in immunocompetent C57BL/6J mice.

Indexed as

CatecholaminesCoated Materials, BiocompatibleMembranes, ArtificialPhosphorylcholineAnimalsDrug ImplantsFibrosisForeign-Body ReactionMiceCatecholaminesCoated Materials, BiocompatibleDrug ImplantsMembranes, ArtificialPhosphorylcholinealginatedopaminefibrosisforeign body responsezwitterionic polymers

Identifiers

PMID27976536
PMCPMC5322155
OpenAlexW2564487662

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.