Evidence map›Paper›PMID 27975145›Full record

ArticleEuropean radiology2017

Dynamic contrast-enhanced MR imaging in predicting progression of enhancing lesions persisting after standard treatment in glioblastoma patients: a prospective study.

Roh-Eul Yoo, Seung Hong Choi, Tae Min Kim, Chul-Kee Park, Sung-Hye Park, Jae-Kyung Won, Il Han Kim, Soon Tae Lee, Hye Jeong Choi, Sung-Hye You and 4 more

Abstract read
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In one paragraph

Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

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  14. AJNR. American journal of neuroradiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Roh-Eul YooDepartment of Radiology, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, 110-744, Seoul, Korea.
Seung Hong ChoiDepartment of Radiology, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, 110-744, Seoul, Korea. verocay@snuh.org.
Tae Min KimDepartment of Internal Medicine, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Chul-Kee ParkDepartment of Neurosurgery, Biomedical Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Sung-Hye ParkDepartment of Pathology, Seoul National University College of Medicine, Seoul, Korea.
Jae-Kyung WonDepartment of Pathology, Seoul National University College of Medicine, Seoul, Korea.
Il Han KimDepartment of Radiation Oncology, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Soon Tae LeeDepartment of Neurology, Seoul National University College of Medicine, Seoul, Korea.
Hye Jeong ChoiDepartment of Radiology, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, 110-744, Seoul, Korea.
Sung-Hye YouDepartment of Radiology, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, 110-744, Seoul, Korea.
Koung Mi KangDepartment of Radiology, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, 110-744, Seoul, Korea.
Tae Jin YunDepartment of Radiology, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, 110-744, Seoul, Korea.
Ji-Hoon KimDepartment of Radiology, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, 110-744, Seoul, Korea.
Chul-Ho SohnDepartment of Radiology, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, 110-744, Seoul, Korea.
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo prospectively explore the value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in predicting the progression of enhancing lesions persisting after standard treatment in patients with surgically resected glioblastoma (GBM).

methodsForty-seven GBM patients, who underwent near-total tumorectomy followed by concurrent chemoradiation therapy (CCRT) with temozolomide (TMZ) between May 2014 and February 2016, were enrolled. Twenty-four patients were finally analyzed for measurable enhancing lesions persisting after standard treatment. DCE-MRI parameters were calculated at enhancing lesions. Mann-Whitney U tests and multivariable stepwise logistic regression were used to compare parameters between progression (n = 16) and non-progression (n = 8) groups.

resultsMean K

conclusionsDCE-MRI may help predict the progression of enhancing lesions persisting after the completion of standard treatment in patients with surgically resected GBM, with mean v KEY POINTS: • Enhancing lesions may persist after standard treatment in GBM patients. • DCE-MRI may help predict the progression of the enhancing lesions. • Mean K

Indexed as

AdultAgedBrain NeoplasmsContrast MediaDisease ProgressionFemaleGlioblastomaHumansLogistic ModelsMagnetic Resonance ImagingMaleMiddle AgedPredictive Value of TestsProspective StudiesSensitivity and SpecificityContrast MediaChemoradiotherapyGlioblastomaMagnetic resonance imagingPerfusionProgression

Identifiers

PMID27975145
OpenAlexW2564077633

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.