Evidence map›Paper›PMID 27974909›Full record

ReviewJournal of medicine and life

Cutaneous complications of molecular targeted therapy used in oncology.

I Lupu, N Voiculescu, N Bacalbasa, I Cojocaru, V Vrancian, C Giurcaneanu

Open access · greenAbstract readReview
In one paragraph

Review in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

I LupuDepartment of Dermatology, "Elias" University Hospital, Bucharest, Romania.
N VoiculescuDepartment of Dermatology, "Elias" University Hospital, Bucharest, Romania; "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
N Bacalbasa"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
I CojocaruDepartment of Dermatology, "Elias" University Hospital, Bucharest, Romania.
V VrancianBucharest University Emergency Hospital, Bucharest, Romania.
C GiurcaneanuDepartment of Dermatology, "Elias" University Hospital, Bucharest, Romania; "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The new molecular targeted therapy has been developed over the past decades by using the molecular targeted molecular changes discovered in specific types of cancer. Unfortunately, most of these agents (epidermal growth factor receptors, multi-targeted small molecule tyrosine kinase inhibitors, monoclonal antibodies) have severe cutaneous adverse reactions, that not only interfere with the patient's quality of life, but also are dose-limiting and may require treatment interruptions. These cutaneous complications and their management must be very well known by any oncologist and dermatologist who treat oncologic patients. ABBREVIATIONS: EGFR = epidermal growth factor receptors, EGFRI = epidermal growth factor receptors inhibitors.

Indexed as

Antibodies, MonoclonalAntineoplastic AgentsErbB ReceptorsHumansMolecular Targeted TherapyNeoplasmsQuality of LifeAntibodies, MonoclonalAntineoplastic AgentsEGFR protein, humanErbB Receptorscutaneous adverse reactionsinhibitors of EGF receptors, oncologymolecular targeted therapy

Identifiers

PMID27974909
PMCPMC5152604
OpenAlexW2565666679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.