ArticleScientific reports2016
Induction of a robust immunity response against novel duck reovirus in ducklings using a subunit vaccine of sigma C protein.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Isolation, identification, and pathogenicity of Novel Duck Reovirus strain from ducklings in China.Poultry science · 2026Article
- Novel duck reovirus σC hijacks the mitochondrial COQ6-CoQ10 axis to drive NLRP3-dependent pyroptosis.PLoS pathogens · 2026Article
- Development of duplex crystal digital PCR (dPCR) assay for detection and differentiation of NDRV and MDRV.Veterinary and animal science · 2025Article
- Whole-genome characterization and evolutionary analysis of a novel duck reovirus isolated fromVeterinary world · 2025Article
- Update on Reovirus Infections in Waterfowls.Animals : an open access journal from MDPI · 2025Review
- Recombinant linear multiple epitopes of σB protein protect Muscovy ducks against novel duck reovirus infection.Frontiers in veterinary science · 2024Article
- Isolation and identification of a novel goose-origin reovirus GD218 and its pathogenicity experiments.Frontiers in veterinary science · 2024Article
- Article
- Efficacy and Immunogenicity of Recombinant Pichinde Virus-Vectored Turkey Arthritis Reovirus Subunit Vaccine.Vaccines · 2022Article
- Novel duck reovirus exhibits pathogenicity to specific pathogen-free chickens by the subcutaneous route.Scientific reports · 2021Article
- Development of a Recombinant Pichinde Virus-Vectored Vaccine against Turkey Arthritis Reovirus and Its Immunological Response Characterization in Vaccinated Animals.Pathogens (Basel, Switzerland) · 2021Article
- The phosphoproteomic responses of duck (Cairna moschata) to classical/novel duck reovirus infections in the spleen tissue.Scientific reports · 2020Article
- Detection of Novel duck reovirus (NDRV) using visual reverse transcription loop-mediated isothermal amplification (RT-LAMP).Scientific reports · 2018Article
- Comparative proteomic analysis revealed complex responses to classical/novel duck reovirus infections in Cairna moschata.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Novel duck reovirus (NDRV) disease emerged in China in 2011 and continues to cause high morbidity and about 5.0 to 50% mortality in ducklings. Currently there are no approved vaccines for the virus. This study aimed to assess the efficacy of a new vaccine created from the baculovirus and sigma C gene against NDRV. In this study, a recombinant baculovirus containing the sigma C gene was constructed, and the purified protein was used as a vaccine candidate in ducklings. The efficacy of sigma C vaccine was estimated according to humoral immune responses, cellular immune response and protection against NDRV challenge. The results showed that sigma C was highly expressed in Sf9 cells. Robust humoral and cellular immune responses were induced in all ducklings immunized with the recombinant sigma C protein. Moreover, 100% protection against lethal challenge with NDRV TH11 strain was observed. Summary, the recombinant sigma C protein could be utilized as a good candidate against NDRV infection.
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