Evidence map›Paper›PMID 27974641›Full record

ArticleMolecular biology of the cell2017

Proper cytoskeletal architecture beneath the plasma membrane of red blood cells requires

Faryal Ijaz, Yasue Hatanaka, Takahiro Hatanaka, Koji Tsutsumi, Takayuki Iwaki, Kazuo Umemura, Koji Ikegami, Mitsutoshi Setou

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Faryal IjazDepartment of Cellular and Molecular Anatomy and International Mass Imaging Center.
Yasue HatanakaMitsubishi Kagaku Institute of Life Sciences, Tokyo 194-8511, Japan.
Takahiro HatanakaMitsubishi Kagaku Institute of Life Sciences, Tokyo 194-8511, Japan.
Koji TsutsumiDepartment of Cellular and Molecular Anatomy and International Mass Imaging Center.
Takayuki IwakiDepartment of Pharmacology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka 431-3192, Japan.
Kazuo UmemuraDepartment of Pharmacology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka 431-3192, Japan.
Koji IkegamiDepartment of Cellular and Molecular Anatomy and International Mass Imaging Center kikegami@hama-med.ac.jp setou@hama-med.ac.jp.
Mitsutoshi SetouDepartment of Cellular and Molecular Anatomy and International Mass Imaging Center kikegami@hama-med.ac.jp setou@hama-med.ac.jp.
Mitsubishi Group (Japan) · JPHamamatsu University School of Medicine · JPImaging Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammalian red blood cells (RBCs) circulate through blood vessels, including capillaries, for tens of days under high mechanical stress. RBCs tolerate this mechanical stress while maintaining their shape because of their elastic membrane skeleton. This membrane skeleton consists of spectrin-actin lattices arranged as quasi-hexagonal units beneath the plasma membrane. In this study, we found that the organization of the RBC cytoskeleton requires tubulin tyrosine ligase-like 4 (

Indexed as

Actin CytoskeletonActinsAnimalsCell MembraneCytoskeletonCytosolErythrocytesMiceMice, KnockoutNucleosome Assembly Protein 1Peptide SynthasesSpectrinActinsNucleosome Assembly Protein 1Peptide SynthasesSpectrintubulin polyglutamylase

Identifiers

PMID27974641
PMCPMC5305260
OpenAlexW2563591873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.