Evidence map›Paper›PMID 27974570›Full record

ArticleJournal of virology2017

Channel-Inactivating Mutations and Their Revertant Mutants in the Envelope Protein of Infectious Bronchitis Virus.

Janet To, Wahyu Surya, To Sing Fung, Yan Li, Carmina Verdià-Bàguena, Maria Queralt-Martin, Vicente M Aguilella, Ding Xiang Liu, Jaume Torres

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. SARS-CoV-2 E protein: Pathogenesis and potential therapeutic development.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Delivery of recombinant SARS-CoV-2 envelope protein into human cells.bioRxiv : the preprint server for biology · 2021
    Article
  9. Article
  10. Review
  11. Biosensors for Point Mutation Detection.Frontiers in bioengineering and biotechnology · 2021
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Janet ToSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Wahyu SuryaSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
To Sing FungSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Yan LiSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Carmina Verdià-BàguenaDepartment of Physics, Laboratory of Molecular Biophysics. Universitat Jaume I, Castelló, Spain.
Maria Queralt-MartinDepartment of Physics, Laboratory of Molecular Biophysics. Universitat Jaume I, Castelló, Spain.
Vicente M AguilellaDepartment of Physics, Laboratory of Molecular Biophysics. Universitat Jaume I, Castelló, Spain.
Ding Xiang LiuSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore dxliu0001@163.com jtorres@ntu.edu.sg.
Jaume TorresSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore dxliu0001@163.com jtorres@ntu.edu.sg.
Nanyang Technological University · SGUniversitat Jaume I · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been shown previously in the severe acute respiratory syndrome coronavirus (SARS-CoV) that two point mutations, N15A and V25F, in the transmembrane domain (TMD) of the envelope (E) protein abolished channel activity and led to

Indexed as

Amino Acid SequenceAnimalsChickensChlorocebus aethiopsConserved SequenceInfectious bronchitis virusIon ChannelsMembrane PotentialsMutationProtein MultimerizationVero CellsViral Envelope ProteinsVirus ReleaseIon ChannelsViral Envelope Proteinschannel activitycoronavirusenvelope proteininfectious bronchitis virusNMR structuresmall membrane protein

Identifiers

PMID27974570
PMCPMC5309962
OpenAlexW2568845464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.