ArticleAge and ageing2017
Common eye diseases in older adults of southern Germany: results from the KORA-Age study.
Article in Age and ageing, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 32 citations in OpenAlex.
- Smartphone-based lightweight AI system for real-time multiple anterior segment disease screening: development and real-world validation.BMC medicine · 2026Article
- The mechanisms, epidemiology, and clinical implications of thyroid hormones and age-related macular degeneration: a narrative review.Frontiers in medicine · 2026Review
- "Dirty Dry Eye"- A waste volume analysis from topical therapy in keratoconjunctivitis sicca.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Modulation of Decellularized Lacrimal Gland Hydrogel Biodegradation by Genipin Crosslinking.Investigative ophthalmology & visual science · 2024Article
- Improving OCT Image Segmentation of Retinal Layers by Utilizing a Machine Learning Based Multistage System of Stacked Multiscale Encoders and Decoders.Bioengineering (Basel, Switzerland) · 2023Article
- Risk of cataract and glaucoma among older persons with diabetes in India: a cross-sectional study based on LASI, Wave-1.Scientific reports · 2023Article
- The burden of ocular morbidities among elderly patients visiting a district healthcare facility in Malawi: A retrospective study.Health science reports · 2023Article
- Effect of Cataract Surgery on Frequency of Falls among Older Persons: A Systematic Review and Meta-Analysis.Journal of ophthalmology · 2021Article
- Polygonum cuspidatum stem extract (PSE) ameliorates dry eye disease by inhibiting inflammation and apoptosis.Journal of exercise nutrition & biochemistry · 2019Article
- Miniaturization in Glaucoma Monitoring and Treatment: A Review of New Technologies That Require a Minimal Surgical Approach.Ophthalmology and therapy · 2019Review
- Optical coherence tomography angiography of the macula and optic nerve head: microvascular density and test-retest repeatability in normal subjects.BMC ophthalmology · 2018Observational
- [Diagnosis of dry eye disease].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2018Article
- The Association Between Variants of Receptor for Advanced Glycation End Products (RAGE) Gene Polymorphisms and Age-Related Macular Degeneration.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Combination of hyaluronic acid, carmellose, and osmoprotectants for the treatment of dry eye disease.Clinical ophthalmology (Auckland, N.Z.) · 2018Review
- [Anatomy and immunology of the eye].Zeitschrift fur Rheumatologie · 2017Review
- Diabetes and risk of glaucoma: systematic review and a Meta-analysis of prospective cohort studies.International journal of ophthalmology · 2017Article
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: a population-based study in the region of Augsburg (Germany, KORA) was used to identify the prevalence of eye diseases and their risk factors in a sample of aged individuals. Methods: data originated from the KORA-Age study collected in 2012 and 822 participants (49.6% women, 50.4% men, aged 68-96 years) were asked standardised questions about eye diseases. Positive answers were validated and specified by treating ophthalmologists. Additional information came from laboratory data. Polymorphic markers were tested for candidate genes. Results: we received validations and specifications for 339 participants. The most frequent eye diseases were cataracts (299 cases, 36%), dry eyes (120 cases, 15%), glaucoma (72 cases, 9%) and age-related macular degeneration (AMD) (68 cases, 8%). Almost all participants suffering from glaucoma or from AMD also had cataracts. Cataract surgery was associated with diabetes (in men; OR = 2.24; 95% confidence interval [CI] 1.11-4.53; P = 0.025) and smoking (in women; OR = 6.77; CI 1.62-28.35; P = 0.009). In men, treatments in airway diseases was associated with cataracts (glucocorticoids: OR = 5.29, CI 1.20-23.37; P = 0.028; sympathomimetics: OR = 4.57, CI 1.39-15.00; P = 0.012). Polymorphisms in two genes were associated with AMD (ARMS2: OR = 2.28, CI 1.48-3.51; P = 0.005; CFH: OR = 2.03, CI 1.35-3.06; P = 0.010). Conclusion: combinations of eye diseases were frequent at old age. The importance of classical risk factors like diabetes, hypertension and airway diseases decreased either due to a survivor bias leaving healthier survivors in the older age group, or due to an increased influence of other up to now unknown risk factors.
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