Evidence map›Paper›PMID 27974077›Full record

ArticlePublic health nutrition2017

Urinary iodine concentration identifies pregnant women as iodine deficient yet school-aged children as iodine sufficient in rural Niger.

Sonja Y Hess, Césaire T Ouédraogo, Rebecca R Young, Ibrahim F Bamba, Sara Stinca, Michael B Zimmermann, K Ryan Wessells

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Public health nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01832688 (Assessment of the Nutritional Status of Pregnant Women in Zinder, Niger and Optimization of Prenatal Care Services), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01832688 completednot on this map

Assessment of the Nutritional Status of Pregnant Women in Zinder, Niger and Optimization of Prenatal Care Services

TypeobservationalSponsorUniversity of California, DavisRan2014 to 2015Enrolled2,306ConditionsPregnancyArmsProgrammatic prenatal care optimization
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Sonja Y Hess1Program in International and Community Nutrition,Department of Nutrition,University of California,Davis,One Shields Avenue,Davis,CA 95616,USA.ORCID http://orcid.org/0000-0002-4661-277X
Césaire T Ouédraogo1Program in International and Community Nutrition,Department of Nutrition,University of California,Davis,One Shields Avenue,Davis,CA 95616,USA.ORCID http://orcid.org/0000-0003-0634-3226
Rebecca R Young1Program in International and Community Nutrition,Department of Nutrition,University of California,Davis,One Shields Avenue,Davis,CA 95616,USA.
Ibrahim F Bamba2Helen Keller International,Niamey,Niger.
Sara Stinca3Laboratory of Human Nutrition,Swiss Federal Institute of Technology,Zurich,Switzerland.
Michael B Zimmermann3Laboratory of Human Nutrition,Swiss Federal Institute of Technology,Zurich,Switzerland.
K Ryan Wessells1Program in International and Community Nutrition,Department of Nutrition,University of California,Davis,One Shields Avenue,Davis,CA 95616,USA.
University of California, Davis · USÉcole Polytechnique Fédérale de Lausanne · CHHelen Keller International · USUnited Nations Children's Fund Niger · NE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess iodine status among pregnant women in rural Zinder, Niger and to compare their status with the iodine status of school-aged children from the same households.

designSeventy-three villages in the catchment area of sixteen health centres were randomly selected to participate in the cross-sectional survey.

settingSalt iodization is mandatory in Niger, requiring 20-60 ppm iodine at the retail level. SUBJECTS: A spot urine sample was collected from randomly selected pregnant women (n 662) and one school-aged child from the same household (n 373). Urinary iodine concentration (UIC) was assessed as an indicator of iodine status in both groups. Dried blood spots (DBS) were collected from venous blood samples of pregnant women and thyroglobulin (Tg), thyroid-stimulating hormone and total thyroxine were measured. Iodine content of household salt samples (n 108) was assessed by titration.

resultsMedian iodine content of salt samples was 5·5 ppm (range 0-41 ppm), 98 % had an iodine content 40 µg/l.

conclusionsIn this region of Niger, most salt is inadequately iodized. UIC in pregnant women indicated iodine deficiency, whereas UIC of school-aged children indicated marginally adequate iodine status. Thus, estimating population iodine status based solely on monitoring of UIC among school-aged children may underestimate the risk of iodine deficiency in pregnant women.

Indexed as

Nutritional StatusRural PopulationAdultChildCross-Sectional StudiesDose-Response Relationship, DrugDried Blood Spot TestingFamily CharacteristicsFemaleFollow-Up StudiesHumansIodineMaleNigerPregnancyPregnancy Complications, HematologicIodineiodized saltSodium Chloride, DietaryThyroglobulinThyrotropinThyroxineIodineNigerPregnant womenSchool-aged childrenThyroglobulinUrinary iodine

Identifiers

PMID27974077
PMCPMC10261634
OpenAlexW2567225296

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.