Evidence map›Paper›PMID 27973692›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2017

Type 2 diabetes mellitus in people with severe mental illness: inequalities by ethnicity and age. Cross-sectional analysis of 588 408 records from the UK.

J Das-Munshi, M Ashworth, M E Dewey, F Gaughran, S Hull, C Morgan, J Nazroo, I Petersen, P Schofield, R Stewart and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

J Das-MunshiDepartment of Health Service and Population Research, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London.
M AshworthDepartment of Primary Care and Public Health Sciences, King's College London, London.
M E DeweyDepartment of Health Service and Population Research, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London.
F GaughranSouth London and Maudsley NHS Foundation Trust, London.
S HullBlizard Institute, Barts and London School of Medicine and Dentistry, London.
C MorganDepartment of Health Service and Population Research, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London.
J NazrooCathie Marsh Institute for Social Research, University of Manchester, Manchester.
I PetersenDepartment of Primary Care and Population Health, University College London, London, UK.
P SchofieldDepartment of Primary Care and Public Health Sciences, King's College London, London.
R StewartDepartment of Health Service and Population Research, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London.
G ThornicroftDepartment of Health Service and Population Research, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London.
M J PrinceDepartment of Health Service and Population Research, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London.
King's College London · GBKing's College School · GBManchester University · USQueen Mary University of London · GBSouth London and Maudsley NHS Foundation Trust · GBUniversity College London · GB

Funding

Medical Research Council MR/K021494/1
6 · The paper itself

Abstract

aimsTo investigate whether the association of severe mental illness with Type 2 diabetes varies by ethnicity and age.

methodsWe conducted a cross-sectional analysis of data from an ethnically diverse sample of 588 408 individuals aged ≥18 years, registered to 98% of general practices (primary care) in London, UK. The outcome of interest was prevalent Type 2 diabetes.

resultsRelative to people without severe mental illness, the relative risk of Type 2 diabetes in people with severe mental illness was greatest in the youngest age groups. In the white British group the relative risks were 9.99 (95% CI 5.34, 18.69) in those aged 18-34 years, 2.89 (95% CI 2.43, 3.45) in those aged 35-54 years and 1.16 (95% CI 1.04, 1.30) in those aged ≥55 years, with similar trends across all ethnic minority groups. Additional adjustment for anti-psychotic prescriptions only marginally attenuated the associations. Assessment of estimated prevalence of Type 2 diabetes in severe mental illness by ethnicity (absolute measures of effect) indicated that the association between severe mental illness and Type 2 diabetes was more marked in ethnic minorities than in the white British group with severe mental illness, especially for Indian, Pakistani and Bangladeshi individuals with severe mental illness.

conclusionsThe relative risk of Type 2 diabetes is elevated in younger populations. Most associations persisted despite adjustment for anti-psychotic prescriptions. Ethnic minority groups had a higher prevalence of Type 2 diabetes in the presence of severe mental illness. Future research and policy, particularly with respect to screening and clinical care for Type 2 diabetes in populations with severe mental illness, should take these findings into account.

Indexed as

AdolescentAdultAgedAge FactorsBangladeshCross-Sectional StudiesDiabetes Mellitus, Type 2Electronic Health RecordsFemaleGeneral PracticeHealth Status DisparitiesHumansIndiaLondonMaleMental Disorders

Identifiers

PMID27973692
PMCPMC5484374
OpenAlexW2567052441

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.