Evidence map›Paper›PMID 27973418›Full record

ReviewPathogens (Basel, Switzerland)2016

Varicella-Zoster Virus Infectious Cycle: ER Stress, Autophagic Flux, and Amphisome-Mediated Trafficking.

Charles Grose, Erin M Buckingham, John E Carpenter, Jeremy P Kunkel

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Unraveling the Connection: Pain and Endoplasmic Reticulum Stress.International journal of molecular sciences · 2024
    Review
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Charles GroseVirology Laboratory, Children's Hospital, University of Iowa, Iowa City, IA 52242, USA. charles-grose@uiowa.edu.
Erin M BuckinghamVirology Laboratory, Children's Hospital, University of Iowa, Iowa City, IA 52242, USA. erin-buckingham@uiowa.edu.
John E CarpenterVirology Laboratory, Children's Hospital, University of Iowa, Iowa City, IA 52242, USA. john-carpenter@uiowa.edu.
Jeremy P KunkelJC Wilt Infectious Diseases Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3L5, Canada. jeremy.kunkel@phac-aspc.gc.ca.
University of Iowa Stead Family Children’s Hospital · USPublic Health Agency of Canada · CA

Funding

Autophagy and ER stress during varicella infectionR01AI089716 · NIAID · UNIVERSITY OF IOWA · PI GROSE, CHARLES F. · 2011 to 2015
$1.9M
NIAID NIH HHS R01 AI089716
6 · The paper itself

Abstract

Varicella-zoster virus (VZV) induces abundant autophagy. Of the nine human herpesviruses, the VZV genome is the smallest (~124 kbp), lacking any known inhibitors of autophagy, such as the herpes simplex virus

Indexed as

autophagycytomegalovirusER-associated degradationglycoproteinsherpes simplex virusunfolded protein responsevaricella-zoster virusXBP1xenophagy

Identifiers

PMID27973418
PMCPMC5198167
OpenAlexW2563025994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.