Evidence map›Paper›PMID 27973405›Full record

ReviewChildren (Basel, Switzerland)2016

Chronic Pain in Children and Adolescents: Diagnosis and Treatment of Primary Pain Disorders in Head, Abdomen, Muscles and Joints.

Stefan J Friedrichsdorf, James Giordano, Kavita Desai Dakoji, Andrew Warmuth, Cyndee Daughtry, Craig A Schulz

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05666921 (Somatic Symptoms, Alexithymia and Styles of Attachment), which is not on this map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
28.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05666921 recruitingnot on this mapstarted 2021, after this paper: background citation

Somatic Symptoms, Alexithymia and Styles of Attachment: a Cross-sectional Study

TypeobservationalSponsorMeyer Children's Hospital IRCCSRan2021 to 2026Enrolled300ConditionsSomatic Symptom DisorderArmspsychological assessment
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 192 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Parent Psychological Flexibility in Pediatric Chronic Pain.Child psychiatry and human development · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Pediatric pain physician workforce: an assessment of supply and demand.Frontiers in pain research (Lausanne, Switzerland) · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Stefan J FriedrichsdorfChildren's Hospitals and Clinics of Minnesota, Minneapolis, MN 55404, USA. Stefan.Friedrichsdorf@childrensMN.org.
James GiordanoGeorgetown University Medical Center, Washington, DC 20057, USA. james.giordano@georgetown.edu.
Kavita Desai DakojiChildren's Hospitals and Clinics of Minnesota, Minneapolis, MN 55404, USA. Kavita.DesaiDakoji@childrensMN.org.
Andrew WarmuthChildren's Hospitals and Clinics of Minnesota, Minneapolis, MN 55404, USA. Andrew.Warmuth@childrensMN.org.
Cyndee DaughtryChildren's Hospitals and Clinics of Minnesota, Minneapolis, MN 55404, USA. Cyndee.Daughtry@childrensMN.org.
Craig A SchulzChildren's Hospitals and Clinics of Minnesota, Minneapolis, MN 55404, USA. Craig.Schulz@childrensMN.org.
Children's Minnesota · USGeorgetown University · USUniversity of Minnesota · USUniversity of Minnesota Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary pain disorders (formerly "functional pain syndromes") are common, under-diagnosed and under-treated in children and teenagers. This manuscript reviews key aspects which support understanding the development of pediatric chronic pain, points to the current pediatric chronic pain terminology, addresses effective treatment strategies, and discusses the evidence-based use of pharmacology. Common symptoms of an underlying pain vulnerability present in the three most common chronic pain disorders in pediatrics: primary headaches, centrally mediated abdominal pain syndromes, and/or chronic/recurrent musculoskeletal and joint pain. A significant number of children with repeated acute nociceptive pain episodes develop chronic pain in addition to or as a result of their underlying medical condition "chronic-on-acute pain." We provide description of the structure and process of our interdisciplinary, rehabilitative pain clinic in Minneapolis, Minnesota, USA with accompanying data in the treatment of chronic pain symptoms that persist beyond the expected time of healing. An interdisciplinary approach combining (1) rehabilitation; (2) integrative medicine/active mind-body techniques; (3) psychology; and (4) normalizing daily school attendance, sports, social life and sleep will be presented. As a result of restored function, pain improves and commonly resolves. Opioids are not indicated for primary pain disorders, and other medications, with few exceptions, are usually not first-line therapy.

Indexed as

adolescentsbiopsychosocialchildrenchronic paininterdisciplinary treatmentpediatric pain clinicprimary pain disorder

Identifiers

PMID27973405
PMCPMC5184817
OpenAlexW2563209251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.