ReviewJournal of musculoskeletal & neuronal interactions2016
A comparison of peripheral imaging technologies for bone and muscle quantification: a technical review of image acquisition.
Review in Journal of musculoskeletal & neuronal interactions, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Bone Quality in Competitive Athletes: A Systematic Review.Journal of musculoskeletal & neuronal interactions · 2023Pooled it
- What are the Effects of Exercise on Trabecular Microarchitecture in Older Adults? A Systematic Review and Meta-analysis of HR-pQCT Studies.Calcified tissue international · 2023Pooled it
- Bone and joint quality remains impaired in long-term controlled acromegaly: an HR-pQCT study.Journal of the Endocrine Society · 2026Article
- Effects of robotic walking on bone and muscle health in youth with neuromotor impairments: a five-participant case series.Frontiers in endocrinology · 2026Article
- Article
- Smaller and thinner long bones in children and adolescents with cerebral palsy and other neuromotor impairments.Frontiers in endocrinology · 2025Article
- Use of noninvasive imaging to identify causes of skeletal fragility in adults with diabetes: a review.JBMR plus · 2024Review
- Deep learning in sex estimation from a peripheral quantitative computed tomography scan of the fourth lumbar vertebra-a proof-of-concept study.Forensic science, medicine, and pathology · 2023Article
- Associations Between Aldosterone-Renin-Ratio and Bone Parameters Derived from Peripheral Quantitative Computed Tomography and Impact Microindentation in Men.Calcified tissue international · 2023Article
- HR-pQCT for the Evaluation of Muscle Quality and Intramuscular Fat Infiltration in Ageing Skeletal Muscle.Journal of personalized medicine · 2022Article
- Validation of High-Resolution peripheral Quantitative Computed Tomography-Derived Achilles Tendon Properties Against Diagnostic Ultrasound.Journal of musculoskeletal & neuronal interactions · 2022Article
- Multi-atlas segmentation and quantification of muscle, bone and subcutaneous adipose tissue in the lower leg using peripheral quantitative computed tomography.Frontiers in physiology · 2022Article
- Article
- Guidelines for the assessment of bone density and microarchitecture in vivo using high-resolution peripheral quantitative computed tomography.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Article
- Patient-Specific Bone Multiscale Modelling, Fracture Simulation and Risk Analysis-A Survey.Materials (Basel, Switzerland) · 2019Review
- Automated skeletal tissue quantification in the lower leg using peripheral quantitative computed tomography.Physiological measurement · 2018Article
- Validation of Peripheral Quantitative Computed Tomography-Derived Thigh Adipose Tissue Subcompartments in Young Girls Using a 3 T MRI Scanner.Journal of clinical densitometry : the official journal of the International Society for Clinical DensitometryArticle
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The choice of an appropriate imaging technique to quantify bone, muscle, or muscle adiposity needs to be guided by a thorough understanding of its competitive advantages over other modalities balanced by its limitations. This review details the technical machinery and methods behind peripheral quantitative computed tomography (pQCT), high-resolution (HR)-pQCT, and magnetic resonance imaging (MRI) that drive successful depiction of bone and muscle morphometry, densitometry, and structure. It discusses a number of image acquisition settings, the challenges associated with using one versus another, and compares the risk-benefits across the different modalities. Issues related to all modalities including partial volume artifact, beam hardening, calibration, and motion assessment are also detailed. The review further provides data and images to illustrate differences between methods to better guide the reader in selecting an imaging method strategically. Overall, investigators should be cautious of the impact of imaging parameters on image signal or contrast-to-noise-ratios, and the need to report these settings in future publications. The effect of motion should be assessed on images and a decision made to exclude prior to segmentation. A more standardized approach to imaging bone and muscle on pQCT and MRI could enhance comparability across studies and could improve the quality of meta-analyses.
Indexed as
Identifiers
27973379PMC5259568What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.