Evidence map›Paper›PMID 27973344›Full record

ArticlePhysics in medicine and biology2017

Objective comparison of lesion detectability in low and medium-energy collimator iodine-123 mIBG images using a channelized Hotelling observer.

Rebecca A Gregory, Iain Murray, Jonathan Gear, Matthew D Aldridge, Daniel Levine, Lucy Fowkes, Wendy A Waddington, Sue Chua, Glenn Flux

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Physics in medicine and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rebecca A GregoryDepartment of Physics, the Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Downs Road, Sutton SM2 5PT, UK.
Iain Murray
Jonathan Gear
Matthew D Aldridge
Daniel Levine
Lucy Fowkes
Wendy A Waddington
Sue Chua
Glenn Flux
Royal Marsden NHS Foundation Trust · GBInstitute of Cancer Research · GBUniversity College London · GB

Funding

Cancer Research UK 16149Cancer Research UK 16464
6 · The paper itself

Abstract

Iodine-123 mIBG imaging is widely regarded as a gold standard for diagnostic studies of neuroblastoma and adult neuroendocrine cancer although the optimal collimator for tumour imaging remains undetermined. Low-energy (LE) high-resolution (HR) collimators provide superior spatial resolution. However due to septal penetration of high-energy photons these provide poorer contrast than medium-energy (ME) general-purpose (GP) collimators. LEGP collimators improve count sensitivity. The aim of this study was to objectively compare the lesion detection efficiency of each collimator to determine the optimal collimator for diagnostic imaging. The septal penetration and sensitivity of each collimator was assessed. Planar images of the patient abdomen were simulated with static scans of a Liqui-Phil

Indexed as

3-IodobenzylguanidineChildHumansNeuroblastomaPhantoms, ImagingPhotonsRadionuclide ImagingROC Curve3-Iodobenzylguanidine

Identifiers

PMID27973344
PMCPMC6050520
OpenAlexW2567152539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.