Evidence map›Paper›PMID 27969060›Full record

ArticleApplied nursing research : ANR2016

Racial discrimination predicts greater systemic inflammation in pregnant African American women.

Carmen Giurgescu, Christopher G Engeland, Thomas N Templin, Shannon N Zenk, Mary Dawn Koenig, Lindsey Garfield

Abstract read
In one paragraph

Article in Applied nursing research : ANR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Racial/Ethnic Discrimination and Cardiometabolic Diseases: A Systematic Review.Journal of racial and ethnic health disparities · 2024
    Pooled it
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  5. Exploring Social and Demographic Factors as Determinants of Intestinal Inflammation in Very Low Birth-Weight Infants.Advances in neonatal care : official journal of the National Association of Neonatal Nurses · 2021
    Trial
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  12. Prenatal chronic inflammation and children's executive function development.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carmen GiurgescuCollege of Nursing, Wayne State University, Detroit, MI, USA, 48202. Electronic address: carmen.giurgescu@wayne.edu.
Christopher G EngelandDepartment of Biobehavioral Health and College of Nursing, Pennsylvania State University, University Park, PA, USA, 16802. Electronic address: cge2@psu.edu.
Thomas N TemplinCollege of Nursing, Wayne State University, Detroit, MI, USA, 48202. Electronic address: ac0410@wayne.edu.
Shannon N ZenkCollege of Nursing, University of Illinois at Chicago, Chicago, IL, USA, 60612. Electronic address: szenk@uic.edu.
Mary Dawn KoenigCollege of Nursing, University of Illinois at Chicago, Chicago, IL, USA, 60612. Electronic address: marydh@uic.edu.
Lindsey GarfieldMarcella Niehoff School of Nursing, Loyola University, Chicago, IL, USA, 60660. Electronic address: lgarfield@luc.edu.

Funding

Pilot Project ProgramP30ES020957 · NIEHS · WAYNE STATE UNIVERSITY · PI RUNGE-MORRIS, MELISSA A · 2014 to 2021
$10.1M
Race Related Stressors and Preterm Birth in African American WomenR03NR010608 · NINR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GIURGESCU, CARMEN · 2008 to 2009
$152k
NIEHS NIH HHS P30 ES020957NINR NIH HHS R03 NR010608
6 · The paper itself

Abstract

purposeChronic exposure to racial discrimination by pregnant African American women may lead to allostatic overload; thereby, predisposing women to systemic inflammation. Thus, the goal of this study was to examine if experiences of racial discrimination are related to systemic inflammation in pregnant African Americans.

methodsA sample of 96 African American women from Chicago completed questionnaires and had blood drawn during the second trimester of pregnancy (19.7±2.5 weeks).

resultsExperiences of racial discrimination were associated with higher cytokine levels of interleukin (IL)-4 (B=2.161, 95% CI = 1.02-3.30, p<.001) and IL-6 (B=1.859, 95% CI=.61-3.11, p=.004) when controlling for covariates.

conclusionThese findings suggest that experiences of racial discrimination may cause physiological wear and tear on the body leading to alteration of immune functions. Nurses should inquire about women's experiences of racial discrimination and make referrals for community or church support groups for women who report racial discrimination.

Indexed as

Black or African AmericanPrejudiceRacismFemaleHumansInflammationPregnancyPregnancy ComplicationsAfrican AmericanCytokinesDepressive symptomsInflammationPregnancyRacial discrimination

Identifiers

PMID27969060
PMCPMC5159450

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.