Evidence map›Paper›PMID 27966893›Full record

ArticleBioconjugate chemistry2017

Enhancing PET Signal at Target Tissue in Vivo: Dendritic and Multimeric Tris(hydroxypyridinone) Conjugates for Molecular Imaging of α

Cinzia Imberti, Samantha Y A Terry, Carleen Cullinane, Fiona Clarke, Georgina H Cornish, Nisha K Ramakrishnan, Peter Roselt, Andrew P Cope, Rodney J Hicks, Philip J Blower and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. EGFR- and Integrin αInternational journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. [Bioconjugate chemistry · 2021
    Article
  13. Article
  14. Review
  15. Article
  16. Manipulating the In Vivo Behaviour ofInternational journal of molecular sciences · 2020
    Article
  17. Article
  18. Tuning the properties of tris(hydroxypyridinone) ligands: efficientDalton transactions (Cambridge, England : 2003) · 2019
    Article
  19. In Vivo Characterization of 4Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Cinzia ImbertiKing's College London , Division of Imaging Sciences and Biomedical Engineering, Fourth Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Samantha Y A TerryKing's College London , Division of Imaging Sciences and Biomedical Engineering, Fourth Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Carleen CullinanePeter MacCallum Cancer Centre , Melbourne, Victoria 3000, Australia.
Fiona ClarkeKing's College London , Academic Department of Rheumatology, Centre for Molecular and Cellular Biology of Inflammation, Faculty of Life Sciences and Medicine, London SE1 1UL, United Kingdom.
Georgina H CornishKing's College London , Academic Department of Rheumatology, Centre for Molecular and Cellular Biology of Inflammation, Faculty of Life Sciences and Medicine, London SE1 1UL, United Kingdom.
Nisha K RamakrishnanKing's College London , Division of Imaging Sciences and Biomedical Engineering, Fourth Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Peter RoseltPeter MacCallum Cancer Centre , Melbourne, Victoria 3000, Australia.
Andrew P CopeKing's College London , Academic Department of Rheumatology, Centre for Molecular and Cellular Biology of Inflammation, Faculty of Life Sciences and Medicine, London SE1 1UL, United Kingdom.
Rodney J HicksPeter MacCallum Cancer Centre , Melbourne, Victoria 3000, Australia.
Philip J BlowerKing's College London , Division of Imaging Sciences and Biomedical Engineering, Fourth Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Michelle T MaKing's College London , Division of Imaging Sciences and Biomedical Engineering, Fourth Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.ORCID 0000-0002-3349-7346
St Thomas' Hospital · GBKing's College London · GBThe University of Melbourne · AUPeter MacCallum Cancer Centre · AU

Funding

Arthritis Research UK 20525Cancer Research UK 16463Versus Arthritis 20525Wellcome Trust 088641Wellcome Trust WT088641/Z/09/Z
6 · The paper itself

Abstract

Tris(hydroxypyridinone) chelators conjugated to peptides can rapidly complex the positron-emitting isotope gallium-68 (

Indexed as

AnimalsArthritis, RheumatoidChelating AgentsFemaleGallium RadioisotopesIntegrin alphaVbeta3JointsMaleMiceMice, Inbred BALB CMice, Inbred C57BLNeoplasmsOligopeptidesPositron-Emission TomographyPyridinesTissue Distribution3-hydroxypyridin-4-onearginyl-glycyl-aspartic acidChelating AgentsGallium RadioisotopesIntegrin alphaVbeta3OligopeptidesPyridines

Identifiers

PMID27966893
PMCPMC5314429
OpenAlexW2558931128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.