Evidence map›Paper›PMID 27966686›Full record

ArticleChemical communications (Cambridge, England)2016

A microchip electrophoresis-based fluorescence signal amplification strategy for highly sensitive detection of biomolecules.

Yingfeng Qin, Liangliang Zhang, Shuting Li, Jingjin Zhao, Yong Huang, Shulin Zhao, Yi-Ming Liu

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yingfeng QinState Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, China. zhaoshulin001@163.com jzhao12@163.com.
Liangliang ZhangState Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, China. zhaoshulin001@163.com jzhao12@163.com.
Shuting LiState Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, China. zhaoshulin001@163.com jzhao12@163.com.
Jingjin ZhaoState Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, China. zhaoshulin001@163.com jzhao12@163.com.
Yong HuangState Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, China. zhaoshulin001@163.com jzhao12@163.com.
Shulin ZhaoState Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, China. zhaoshulin001@163.com jzhao12@163.com.ORCID 0000-0002-2560-042X
Yi-Ming LiuDepartment of Chemistry and Biochemistry, Jackson State University, 1400 Lynch St., Jackson, MS 39217, USA.
Guangxi Normal University · CNJackson State University · US

Funding

Microfluidic mass spectrometry based fast chemical characterization of exosomesSC1GM089557 · NIGMS · JACKSON STATE UNIVERSITY · PI LIU, YIMING · 2010 to 2018
$1.4M
NIGMS NIH HHS SC1 GM089557
6 · The paper itself

Abstract

We have developed a microchip electrophoresis (MCE)-based fluorescence signal amplification strategy as a universal MCE method for the detection of trace biomolecules. This strategy exhibits high sensitivity and specificity for target molecules, and has been applied for the detection of interferon-gamma (IFN-γ) in human plasma with satisfactory results.

Indexed as

Limit of DetectionElectrophoresis, MicrochipHumansInterferon-gammaSpectrometry, FluorescenceInterferon-gamma

Identifiers

PMID27966686
PMCPMC5446791
OpenAlexW2559779067

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.