ArticleScientific reports2016
Epidemiology of two human protoparvoviruses, bufavirus and tusavirus.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Global Status of Bufavirus, Cosavirus, and Saffold Virus in Gastroenteritis: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Livestock aggregated samples for monitoring viruses infecting animals and potentially zoonotic viral pathogens.One health (Amsterdam, Netherlands) · 2026Article
- First genomic evidence and molecular epidemiology of porcine bufavirus in Myanmar: Whole-genome characterization, phylogenetic insights, and potential zoonotic implications.Veterinary world · 2025Article
- Genoprevalence of cutavirus in benign and malignant intestinal and breast tissues.The Journal of general virology · 2025Article
- Decreases in chimpanzee respiratory disease signs and enteric viral quantity following implementation of anthroponotic disease prevention protocols at a long-term research site.Biological conservation · 2025Article
- Genomic Characterization and Molecular Epidemiology of Tusaviruses and Related Novel Protoparvoviruses (FamilyViruses · 2025Article
- Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes.Viruses · 2024Article
- Incidental finding of a human-like tusavirus in a lamb with lip lesions and fatal pneumonia.The Journal of general virology · 2024Article
- First detection and genetic characterization of canine bufavirus in domestic dogs, Thailand.Scientific reports · 2024Article
- Molecular Surveillance for Bocaparvoviruses and Bufaviruses in the European Hedgehog (Microorganisms · 2024Article
- Old and Novel Enteric Parvoviruses of Dogs.Pathogens (Basel, Switzerland) · 2023Review
- First report of canine bufavirus in India.Archives of virology · 2022Article
- Emerging Respiratory Viruses of Cats.Viruses · 2022Review
- Investigation of Bufavirus and Parvovirus 4 in Patients with Gastro-Enteritis from the South-East of France.Pathogens (Basel, Switzerland) · 2021Article
- Emerging Parvoviruses in Domestic Cats.Viruses · 2021Review
- Human Protoparvovirus DNA and IgG in Children and Adults with and without Respiratory or Gastrointestinal Infections.Viruses · 2021Article
- Article
- Structural Characterization of Cuta- and Tusavirus: Insight into Protoparvoviruses Capsid Morphology.Viruses · 2020Article
- Review
- Global Distribution of Human Protoparvoviruses.Emerging infectious diseases · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two human parvoviruses were recently discovered by metagenomics in Africa, bufavirus (BuV) in 2012 and tusavirus (TuV) in 2014. These viruses have been studied exclusively by PCR in stool and detected only in patients with diarrhoea, although at low prevalence. Three genotypes of BuV have been identified. We detected, by in-house EIA, BuV1-3 IgG antibodies in 7/228 children (3.1%) and 10/180 adults (5.6%), whereas TuV IgG was found in one child (0.4%). All children and 91% of the adults were Finnish, yet interestingly 3/6 adults of Indian origin were BuV-IgG positive. By competition EIA, no cross-reactivity between the BuVs was detected, indicating that the BuV genotypes represent distinct serotypes. Furthermore, we analysed by BuV qPCR stool and nasal swab samples from 955 children with gastroenteritis, respiratory illness, or both, and found BuV DNA in three stools (0.3%) and for the first time in a nasal swab (0.1%). This is the first study documenting the presence of BuV and TuV antibodies in humans. Although the seroprevalences of both viruses were low in Finland, our results indicate that BuV infections might be widespread in Asia. The BuV-specific humoral immune responses appeared to be strong and long-lasting, pointing to systemic infection in humans.
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Registered trials
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