Evidence map›Paper›PMID 27966473›Full record

ArticleNanotechnology2017

Optical properties of biomimetic probes engineered from erythrocytes.

Joshua M Burns, Rolf Saager, Boris Majaron, Wangcun Jia, Bahman Anvari

Open access · greenAbstract read
In one paragraph

Article in Nanotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. RBC-Derived Optical Nanoparticles Remain Stable After a Freeze-Thaw Cycle.Langmuir : the ACS journal of surfaces and colloids · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Joshua M BurnsDepartment of Bioengineering, University of California, Riverside, CA 92521, USA.
Rolf SaagerBeckman Laser Institute and Medical Clinic, University of California, Irvine, CA 92612, USA.
Boris MajaronDepartment of Complex Matter, Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana, Slovenia.
Wangcun JiaBeckman Laser Institute and Medical Clinic, University of California, Irvine, CA 92612, USA.
Bahman AnvariDepartment of Bioengineering, University of California, Riverside, CA 92521, USA.
Beckman Laser Institute and Medical Clinic · USJožef Stefan Institute · SIUniversity of California, Irvine · USUniversity of California, Riverside · US

Funding

Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI DURKIN, ANTHONY · 2012 to 2017
$7.0M
Erythrocyte-derived particles for near infrared phototherapy of port wine stains.R01AR068067 · NIAMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Bahman Anvari, JOHN STUART NELSON · 2016 to 2026
$3.3M
NIAMS NIH HHS R01 AR068067NIBIB NIH HHS P41 EB015890
6 · The paper itself

Abstract

Light-activated theranostic materials offer a potential platform for optical imaging and phototherapeutic applications. We have engineered constructs derived from erythrocytes, which can be doped with the FDA-approved near infrared (NIR) chromophore, indocyanine green (ICG). We refer to these constructs as NIR erythrocyte-mimicking transducers (NETs). Herein, we investigated the effects of changing the NETs mean diameter from micron- (≈4 μm) to nano- (≈90 nm) scale, and the ICG concentration utilized in the fabrication of NETs from 5 to 20 μM on the resulting absorption and scattering characteristics of the NETs. Our approach consisted of integrating sphere-based measurements of light transmittance and reflectance, and subsequent utilization of these measurements in an inverse adding-doubling algorithm to estimate the absorption (μ

Indexed as

AnimalsBiomimetic MaterialsCattleErythrocytesIndocyanine GreenLightMolecular ProbesMonte Carlo MethodOptical ImagingOptics and PhotonicsScattering, RadiationSpectroscopy, Near-InfraredTheranostic NanomedicineTransducersIndocyanine GreenMolecular Probes

Identifiers

PMID27966473
PMCPMC5189990
OpenAlexW2566408528

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.