ReviewHemodialysis international. International Symposium on Home Hemodialysis2017
Can twice weekly hemodialysis expand patient access under resource constraints?
Review in Hemodialysis international. International Symposium on Home Hemodialysis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- Incremental Hemodialysis Practices and Impact on Survival: Systematic Review and Meta-Analysis.Kidney medicine · 2026Article
- Frequency of ED visits and mortality among the adults with ESRD on twice-weekly maintenance hemodialysis at tertiary care hospital in Bhutan.International journal of emergency medicine · 2025Article
- Adequacy of haemodialysis and associated factors among patients with end-stage kidney disease in Tanzania.Journal of Taibah University Medical Sciences · 2024Article
- Effect of Membrane Permeance and System Parameters on the Removal of Protein-Bound Uremic Toxins in Hemodialysis.Annals of biomedical engineering · 2024Article
- Cost analysis of the management of end-stage renal disease patients in Abuja, Nigeria.Cost effectiveness and resource allocation : C/E · 2023Article
- Bedside rationing and moral distress in nephrologists in sub- Saharan Africa.BMC nephrology · 2022Article
- Cost of illness of chronic kidney disease in Lebanon: from the societal and third-party payer perspectives.BMC health services research · 2022Article
- Dialysis Service in the Embattled Tigray Region of Ethiopia: A Call to Action.International journal of nephrology · 2022Article
- Comparison of nutritional and hydration status in patients undergoing twice and thrice-weekly hemodialysis: a silent drama in developing countries.International urology and nephrology · 2021Observational
- Sustainable Development Goals relevant to kidney health: an update on progress.Nature reviews. Nephrology · 2021Review
- Ethical challenges in nephrology: a call for action.Nature reviews. Nephrology · 2020Review
- Twice-Weekly Hemodialysis Is an Option for Many Patients in Times of Dialysis Unit Stress.Journal of the American Society of Nephrology : JASN · 2020Article
- Developing the ethical framework of end-stage kidney disease care: from practice to policy.Kidney international supplements · 2020Review
- Hemodialysis Adequacy and Its Impact on Long-Term Patient Survival in Demographically, Socially, and Culturally Homogeneous Patients.International journal of nephrology · 2020Article
- Inpatient Dialysis Planning During the COVID-19 Pandemic: A Single-Center Experience and Review of the Literature.International journal of nephrology and renovascular disease · 2020Article
- Observational
- The strange case of Mr. H. Starting dialysis at 90 years of age: clinical choices impact on ethical decisions.BMC medical ethics · 2017Article
- Factors associated with the malnutrition inflammation score (MIS) among hemodialysis patients in Dhaka city: a cross-sectional study in tertiary care hospitals.Porto biomedical journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The convention of prescribing hemodialysis on a thrice weekly schedule began empirically when it seemed that this frequency was convenient and likely to treat symptoms for a majority of patients. Later, when urea was identified as the main target and marker of clearance, studies supported the prevailing notion that thrice weekly dialysis provided appropriate clearance of urea. Today, national guidelines on hemodialysis from most countries recommend patients receive at least thrice weekly therapy. However, resource constraints in low- and middle-income countries (LMIC) have resulted in a substantial proportion of patients using less frequent hemodialysis in these settings. Observational studies of patients on twice weekly dialysis show that twice weekly therapy has noninferior survival rates compared with thrice weekly therapy. In fact, models of urea clearance also show that twice weekly therapy can meet urea clearance "targets" if patients have significant residual function or if they follow a protein-restricted diet, as may be common in LMIC. Greater reliance on twice weekly therapy, at least at the start of hemodialysis, therefore has potential to reduce health care costs and increase access to renal replacement therapy in low-resource settings; however, randomized control trials are needed to better understand long-term outcomes of twice versus thrice weekly therapy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.