ArticleSleep & breathing = Schlaf & Atmung2017
Severity of individual obstruction events is gender dependent in sleep apnea.
Article in Sleep & breathing = Schlaf & Atmung, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Sleep-disordered breathing and the risk of cognitive decline: a meta-analysis of 19,940 participants.Sleep & breathing = Schlaf & Atmung · 2018Pooled it
- Advances in the Diagnosis and Treatment of Obstructive Sleep Apnea in Women.Pulmonary therapy · 2026Review
- A Two-Level Ensemble Machine Learning Framework for OSA Classification Whilst Awake from Noisy Tracheal Breathing Sounds.Sensors (Basel, Switzerland) · 2026Article
- Analysis of differential photoplethysmography signal patterns in apnea and hypopnea.Physiological measurement · 2026Article
- Article
- Improving the cardiovascular outcomes of obstructive sleep apnea: Towards more precise hypoxia-based models of disease severity.Current sleep medicine reports · 2025Article
- Gender differences in obstructive sleep apnea syndrome: a pilot study.Sleep & breathing = Schlaf & Atmung · 2024Article
- Chronic intermittent hypoxia-induced hypertension: the impact of sex hormones.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Review
- Outcomes in Patients with Acute Myocardial Infarction and Known Sleep Apnea: A Nationwide Analysis.Journal of clinical medicine · 2023Article
- International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023Review
- Article
- Review
- Smoking and sleep apnea duration mediated the sex difference in daytime sleepiness in OSA patients.Sleep & breathing = Schlaf & Atmung · 2021Article
- Polysomnographic characteristics of severe obstructive sleep apnea vary significantly between hypertensive and normotensive patients of both genders.Sleep & breathing = Schlaf & Atmung · 2021Article
- Evaluation of Obstructive Sleep Apnea in Female Patients in Primary Care: Time for Improvement?Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2021Review
- Longer apneas and hypopneas are associated with greater ultra-short-term HRV in obstructive sleep apnea.Scientific reports · 2020Article
- Increased nocturnal arterial pulsation frequencies of obstructive sleep apnoea patients is associated with an increased number of lapses in a psychomotor vigilance task.ERJ open research · 2020Article
- Severity of Desaturations Reflects OSA-Related Daytime Sleepiness Better Than AHI.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn obstructive sleep apnea (OSA), severity of individual obstruction events is connected to increased mortality rate and it can be significantly different in patients with similar apnea-hypopnea index (AHI). However, possible gender-dependent variation in severity of obstruction events in different OSA categories is unknown. We investigated whether the severity of obstruction events differs between genders with similar AHI and if this difference varies between OSA categories.
methodsPolygraphic recordings of 2057 consecutive patients with suspected OSA were reanalyzed and those with AHI ≥5/h were included for further analysis (n
resultsApneas were 16.9 and 19.6% longer (MWU p ≤ 0.015, GLM p ≤ 0.036) and desaturation areas were 15.4 and 23.7% larger (MWU p ≤ 0.024, GLM p ≤ 0.053) in males compared to females with moderate and severe OSA, respectively. In contrast, hypopneas were 9.1% shorter (MWU p = 0.001, GLM p ≤ 0.001) and desaturation areas were 6.0% smaller (MWU p = 0.114, GLM p = 0.025) in men with mild OSA. The apnea index was 433.3 and 313.1% higher (MWU p ≤ 0.001, GLM p ≤ 0.043) and the hypopnea index was 12.2 and 17.8% lower (MWU p ≤ 0.001, GLM p = 0.002, p = 0.083) in males with mild and moderate OSA, respectively.
conclusionAs severity of individual obstruction events was significantly different in males and females, the overall severity of OSA may not be similar despite the similarity in AHI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.