Evidence map›Paper›PMID 27966040›Full record

ArticleEuropean radiology2017

Diagnostic performance of calcification-suppressed coronary CT angiography using rapid kilovolt-switching dual-energy CT.

Hiroto Yunaga, Yasutoshi Ohta, Yasuhiro Kaetsu, Shinichiro Kitao, Tomomi Watanabe, Yoshiyuki Furuse, Kazuhiro Yamamoto, Toshihide Ogawa

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hiroto YunagaDivision of Radiology, Department of Pathophysiological Therapeutic Science, Faculty of Medicine, Tottori University, 36-1, Nishi-cho, Yonago City, Tottori, 683-8504, Japan. yunagahiroto@gmail.com.
Yasutoshi OhtaDivision of Radiology, Department of Pathophysiological Therapeutic Science, Faculty of Medicine, Tottori University, 36-1, Nishi-cho, Yonago City, Tottori, 683-8504, Japan.
Yasuhiro KaetsuDepartment of Cardiology, Kakogawa Higashi Hospital, Kakogawa, Japan.
Shinichiro KitaoDivision of Radiology, Department of Pathophysiological Therapeutic Science, Faculty of Medicine, Tottori University, 36-1, Nishi-cho, Yonago City, Tottori, 683-8504, Japan.
Tomomi WatanabeDivision of Cardiology, Department of Molecular Medicine and Therapeutics, Faculty of Medicine, Tottori University, Yonago, Japan.
Yoshiyuki FuruseDivision of Cardiology, Department of Molecular Medicine and Therapeutics, Faculty of Medicine, Tottori University, Yonago, Japan.
Kazuhiro YamamotoDivision of Cardiology, Department of Molecular Medicine and Therapeutics, Faculty of Medicine, Tottori University, Yonago, Japan.
Toshihide OgawaDivision of Radiology, Department of Pathophysiological Therapeutic Science, Faculty of Medicine, Tottori University, 36-1, Nishi-cho, Yonago City, Tottori, 683-8504, Japan.
Tottori University · JPEdogawa Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMulti-detector-row computed tomography angiography (MDCTA) plays an important role in the assessment of patients with suspected coronary artery disease. However, MDCTA tends to overestimate stenosis in calcified coronary artery lesions. The aim of our study was to evaluate the diagnostic performance of calcification-suppressed material density (MD) images produced by using a single-detector single-source dual-energy computed tomography (ssDECT).

methodsWe enrolled 67 patients with suspected or known coronary artery disease who underwent ssDECT with rapid kilovolt-switching (80 and 140 kVp). Coronary artery stenosis was evaluated on the basis of MD images and virtual monochromatic (VM) images. The diagnostic performance of the two methods for detecting coronary artery disease was compared with that of invasive coronary angiography as a reference standard.

resultsWe evaluated 239 calcified segments. In all the segments, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy for detecting significant stenosis were respectively 88%, 88%, 75%, 95% and 88% for the MD images, 91%, 71%, 56%, 95% and 77% for the VM images. PPV was significantly higher on the MD images than on the VM images (P < 0.0001).

conclusionsCalcification-suppressed MD images improved PPV and diagnostic performance for calcified coronary artery lesions. KEY POINTS: • Computed tomography angiography tends to overestimate stenosis in calcified coronary artery. • Dual-energy CT enables us to suppress calcification of coronary artery lesions. • Calcification-suppressed material density imaging reduces false-positive diagnosis of calcified lesion.

Indexed as

AgedComputed Tomography AngiographyCoronary AngiographyCoronary StenosisCoronary VesselsFemaleHumansMaleMiddle AgedMultidetector Computed TomographyRadiography, Dual-Energy Scanned ProjectionReference StandardsReproducibility of ResultsVascular CalcificationCoronary angiographyCoronary vesselsRadiography, dual-energy scanned projectionTomography, X-ray computedVascular calcification

Identifiers

PMID27966040
OpenAlexW2565103853

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.