Evidence map›Paper›PMID 27966039›Full record

ArticlePediatric radiology2017

Magnetic resonance tissue phase mapping demonstrates altered left ventricular diastolic function in children with chronic kidney disease.

Charlotte Gimpel, Bernd A Jung, Sabine Jung, Johannes Brado, Daniel Schwendinger, Barbara Burkhardt, Martin Pohl, Katja E Odening, Julia Geiger, Raoul Arnold

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Article in Pediatric radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. A comprehensive characterization of myocardial and vascular phenotype in pediatric chronic kidney disease using cardiovascular magnetic resonance imaging.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018
    Article
  6. Article
  7. Review
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Charlotte GimpelDepartment of General Pediatrics, Adolescent Medicine and Neonatology, Center for Pediatrics, Medical Center - University of Freiburg, Mathildenstr. 1, 79106,, Freiburg, Germany. Charlotte.Gimpel@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0003-1296-9081
Bernd A JungInstitute of Diagnostic, Interventional and Pediatric Radiology, Inselspital Bern, Bern, Switzerland.
Sabine JungDepartment of Nuclear Medicine, Medical Center - University of Freiburg, Freiburg, Germany.
Johannes BradoDepartment of Cardiology and Angiology I, University Heart Center Freiburg, Freiburg, Germany.
Daniel SchwendingerUniversity Children's Hospital Zurich, Zurich, Switzerland.
Barbara BurkhardtPediatric Heart Center, University Children's Hospital Zurich, Zurich, Switzerland.
Martin PohlDepartment of General Pediatrics, Adolescent Medicine and Neonatology, Center for Pediatrics, Medical Center - University of Freiburg, Mathildenstr. 1, 79106,, Freiburg, Germany.
Katja E OdeningDepartment of Cardiology and Angiology I, University Heart Center Freiburg, Freiburg, Germany.
Julia GeigerDepartment of Radiology, University Children's Hospital Zurich, Zurich, Switzerland.
Raoul ArnoldDepartment of Pediatric and Congenital Cardiology, University Hospital Heidelberg, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEchocardiographic examinations have revealed functional cardiac abnormalities in children with chronic kidney disease.

objectiveTo assess the feasibility of MRI tissue phase mapping in children and to assess regional left ventricular wall movements in children with chronic kidney disease. MATERIALS AND

methodsTwenty pediatric patients with chronic kidney disease (before or after renal transplantation) and 12 healthy controls underwent tissue phase mapping (TPM) to quantify regional left ventricular function through myocardial long (Vz) and short-axis (Vr) velocities at all 3 levels of the left ventricle.

resultsPatients and controls (age: 8 years-20 years) were matched for age, height, weight, gender and heart rate. Patients had higher systolic blood pressure. No patient had left ventricular hypertrophy on MRI or diastolic dysfunction on echocardiography. Fifteen patients underwent tissue Doppler echocardiography, with normal z-scores for mitral early diastolic (V

conclusionTissue phase mapping is feasible in children and adolescents. Children with chronic kidney disease show significantly reduced peak diastolic long- and short-axis left ventricular wall velocities, reflecting impaired early diastolic filling. Thus, tissue phase mapping detects chronic kidney disease-related functional myocardial changes before overt left ventricular hypertrophy or echocardiographic diastolic dysfunction occurs.

Indexed as

AdolescentCase-Control StudiesChildEchocardiography, DopplerFemaleHumansKidney TransplantationMaleRenal Insufficiency, ChronicVentricular Dysfunction, LeftYoung AdultAdolescentsCardiac imaging techniqueCardio renal syndromeChronic renal failureLeft ventricular dysfunctionMagnetic resonance imagingTissue phase mapping

Identifiers

PMID27966039

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.