ReviewFrontiers in veterinary science2016
Challenges of Generating and Maintaining Protective Vaccine-Induced Immune Responses for Foot-and-Mouth Disease Virus in Pigs.
Review in Frontiers in veterinary science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Oral levamisole as a route-decoupled adjunct to intramuscular foot-and-mouth disease vaccination: a two-species evaluation.Frontiers in veterinary science · 2026Article
- Robust cross-immunity against a heterologous field strain of foot-and-mouth disease virus achieved in small ruminants following commercial vaccination in Jordan.Frontiers in veterinary science · 2026Article
- The pathogenesis of foot-and-mouth disease virus: current understandings and knowledge gaps.Veterinary research · 2025Review
- Remapping the spatial distribution of neutralizing sites and their immunodominance on the capsid of different topotypes of FMDV serotype O by site-directed competitive ELISA for detection of neutralizing antibodies.Microbiology spectrum · 2025Article
- Foot-and-mouth disease: genomic and proteomic structure, antigenic sites, serotype relationships, immune evasion, recent vaccine development strategies, and future perspectives.Veterinary research · 2025Review
- Article
- Modeling target-density-based cull strategies to contain foot-and-mouth disease outbreaks.PeerJ · 2024Article
- Compared to Aluminum Hydroxide Adjuvant, Montanide ISA 206 VG Induces a Higher and More Durable Neutralizing Antibody Response against FMDV in Goats.Archives of Razi Institute · 2023Article
- Evaluation of the effectiveness of foot-and-mouth disease vaccination of animals in the buffer zone of the Republic of Armenia in 2016-2020.BMC veterinary research · 2023Article
- Vaccination Failures in Pigs-The Impact of Chosen Factors on the Immunisation Efficacy.Vaccines · 2023Review
- Combined Adjuvant Formulations Enhanced an Immune Response of Trivalent Foot and Mouth Disease Vaccine in Cattle.Veterinary medicine (Auckland, N.Z.) · 2023Article
- Toward the calibration of serological assays using sera collected from cattle and sheep following a single dose of foot-and-mouth disease vaccine.Veterinary world · 2022Article
- The Potential Adjuvanticity of CAvantVaccines · 2021Article
- Scale-Up Production of Type O and A Foot-and-Mouth Disease Bivalent Vaccine and Its Protective Efficacy in Pigs.Vaccines · 2021Article
- Post-vaccination Monitoring to Assess Foot-and-Mouth Disease Immunity at Population Level in Korea.Frontiers in veterinary science · 2021Article
- Evaluation of Potency and Duration of Immunity Elicited by a Multivalent FMD Vaccine for Use in South Africa.Frontiers in veterinary science · 2021Article
- Article
- A Single Dose of Dendrimer BVaccines · 2020Article
- Farmers' willingness to pay for foot and mouth disease vaccine in different cattle production systems in Amhara region of Ethiopia.PloS one · 2020Article
- Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vaccination can play a central role in the control of outbreaks of foot-and-mouth disease (FMD) by reducing both the impact of clinical disease and the extent of virus transmission between susceptible animals. Recent incursions of exotic FMD virus lineages into several East Asian countries have highlighted the difficulties of generating and maintaining an adequate immune response in vaccinated pigs. Factors that impact vaccine performance include (i) the potency, antigenic payload, and formulation of a vaccine; (ii) the antigenic match between the vaccine and the heterologous circulating field strain; and (iii) the regime (timing, frequency, and herd-level coverage) used to administer the vaccine. This review collates data from studies that have evaluated the performance of foot-and-mouth disease virus vaccines at the individual and population level in pigs and identifies research priorities that could provide new insights to improve vaccination in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.