Evidence map›Paper›PMID 27965796›Full record

ArticlePilot and feasibility studies2015

Exploring the Determinants of Suicidal Behavior: Conventional and Emergent Risk (DISCOVER): a feasibility study.

Zainab Samaan, Monica Bawor, Brittany B Dennis, Wala El-Sheikh, Jane DeJesus, Sumathy Rangarajan, Judith Vair, Heather Sholer, Nicole Hutchinson, Elizabeth Iordan and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pilot and feasibility studies, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Zainab SamaanDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON Canada ; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON Canada ; Population Genomics Program, Chanchlani Research Centre, McMaster University, Hamilton, ON Canada ; MiNDS Neuroscience Program, McMaster University, Hamilton, ON Canada ; Population Health Research Institute, Hamilton Health Sciences/McMaster University, Hamilton, ON Canada ; St. Joseph's Healthcare Hamilton, 100 West 5th Street, Hamilton, ON L8N 3K7 Canada.
Monica BaworPopulation Genomics Program, Chanchlani Research Centre, McMaster University, Hamilton, ON Canada ; MiNDS Neuroscience Program, McMaster University, Hamilton, ON Canada.
Brittany B DennisDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON Canada ; Population Genomics Program, Chanchlani Research Centre, McMaster University, Hamilton, ON Canada.
Wala El-SheikhPopulation Health Research Institute, Hamilton Health Sciences/McMaster University, Hamilton, ON Canada.
Jane DeJesusPopulation Health Research Institute, Hamilton Health Sciences/McMaster University, Hamilton, ON Canada.
Sumathy RangarajanPopulation Health Research Institute, Hamilton Health Sciences/McMaster University, Hamilton, ON Canada.
Judith VairSt. Joseph's Healthcare Hamilton, 100 West 5th Street, Hamilton, ON L8N 3K7 Canada.
Heather SholerSt. Joseph's Healthcare Hamilton, 100 West 5th Street, Hamilton, ON L8N 3K7 Canada.
Nicole HutchinsonSt. Joseph's Healthcare Hamilton, 100 West 5th Street, Hamilton, ON L8N 3K7 Canada.
Elizabeth IordanSt. Joseph's Healthcare Hamilton, 100 West 5th Street, Hamilton, ON L8N 3K7 Canada.
Pam MackiePopulation Health Research Institute, Hamilton Health Sciences/McMaster University, Hamilton, ON Canada.
Shofiqul IslamPopulation Health Research Institute, Hamilton Health Sciences/McMaster University, Hamilton, ON Canada.
Mahshid DeghanPopulation Health Research Institute, Hamilton Health Sciences/McMaster University, Hamilton, ON Canada.
Jennifer BraschDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON Canada ; St. Joseph's Healthcare Hamilton, 100 West 5th Street, Hamilton, ON L8N 3K7 Canada.
Lehana ThabaneDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON Canada ; Population Health Research Institute, Hamilton Health Sciences/McMaster University, Hamilton, ON Canada ; St. Joseph's Healthcare Hamilton, 100 West 5th Street, Hamilton, ON L8N 3K7 Canada ; Biostatistics Unit, Centre for Evaluation of Medicine, Hamilton, ON Canada ; System Linked Research Unit, Hamilton, ON Canada.
McMaster University · CASt. Joseph’s Healthcare Hamilton · CAHamilton Health Sciences · CAPopulation Health Research Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSuicidal behavior is a growing public health concern resulting in morbidity and premature death. Although certain factors such as age, sex, and psychiatric disorders have been consistently reported to be associated with suicidal behavior, other factors including biological markers, diet, and physical activity may also influence suicidal behavior. The purpose of this pilot study was to evaluate the feasibility of conducting a full-scale study to identify the conventional and novel risk factors of suicidal behavior in individuals who made a recent suicide attempt.

methodsThis pilot study was a case-control study of participants with recent (within 1 month of admission) suicide attempts admitted to hospital and compared to two control groups: 1) psychiatric inpatient participants without a history of suicide attempts and 2) community-based controls. We collected information on demographic variables, circumstances of suicide attempts (for cases), medical and psychiatric diagnoses, behavioral patterns, physical measurements, and social factors. Blood and urine samples were also collected for biological markers. Feasibility outcomes are as follows: 1) 50 % of all eligible cases will consent to participate, 2) 50 cases and 100 controls per year can be recruited, and 3) at least 80 % of the participants will provide blood samples for DNA and biological markers.

resultsWe recruited 179 participants in total; 51 cases, 57 psychiatric controls without suicide attempt, and 71 non-psychiatric controls in Hamilton, Ontario. Recruitment rate was 70 % (213/304), and we obtained urine and blood specimens from 90 % (191/213) of participants. Questionnaire completion rates were high, and data quality was very good with few data-related queries to resolve. We learned that cases tended to be hospitalized for long periods of time and the suicide attempt occurred more than a month ago in many of the cases; therefore, we expanded our inclusion criterion related to timing of suicide attempt to 3 months instead of 1 month.

conclusionsThe study procedures needed certain modifications including extending the time between suicide attempt and date of recruitment, and more detailed questionnaires related to diet were necessary while other questionnaires such as social support needed to be shortened. Overall, this study showed that it is feasible to conduct a larger-scale study.

Indexed as

BiomarkersPilot studyRisk factorsSocial determinantsSuicidal behaviorSuicide

Identifiers

PMID27965796
PMCPMC5154080
OpenAlexW2158636313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.