Activated IL-1RI Signaling Pathway Induces Th17 Cell Differentiation

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

28 citing papers in PubMed, 38 citations in OpenAlex.

1. Molecular Signature and miRNA Pattern of CD4 + T Lymphocytes in Plaque Psoriasis.Clinical reviews in allergy & immunology · 2026
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2. Autophagy-NLRP3 Inflammasome Crosstalk in Microglia: A Therapeutic Target for Multiple Sclerosis.Inflammation · 2026
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3. Tinea labialis in a patient with Schnitzler syndrome on interleukin-1 receptor antagonist.JAAD case reports · 2025
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4. OCA-B promotes pathogenic maturation of stem-like CD4+ T cells and autoimmune demyelination.The Journal of clinical investigation · 2025
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5. The multiple roles of interferon regulatory factor family in health and disease.Signal transduction and targeted therapy · 2024
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6. IL-1 Receptor Dynamics in Immune Cells: Orchestrating Immune Precision and Balance.Immune network · 2024
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7. Soluble P2X7 Receptor Plasma Levels in Obese Subjects before and after Weight Loss via Bariatric Surgery.International journal of molecular sciences · 2023
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8. Regulatory effects of IRF4 on immune cells in the tumor microenvironment.Frontiers in immunology · 2023
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9. Impact of ROS-Dependent Lipid Metabolism on Psoriasis Pathophysiology.International journal of molecular sciences · 2022
   Review
10. The Therapeutic Prospects of Targeting IL-1R1 for the Modulation of Neuroinflammation in Central Nervous System Disorders.International journal of molecular sciences · 2022
    Review
11. TNF plays a crucial role in inflammation by signaling via T cell TNFR2.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
12. Genetic and immunological contributors to virus-induced paralysis.Brain, behavior, & immunity - health · 2021
    Article
13. Induction of Unique STAT Heterodimers by IL-21 Provokes IL-1RI Expression on CD8Immune network · 2021
    Article
14. Metformin ameliorates scleroderma via inhibiting Th17 cells and reducing mTOR-STAT3 signaling in skin fibroblasts.Journal of translational medicine · 2021
    Article
15. Th17 Cells in Periodontitis and Its Regulation by A20.Frontiers in immunology · 2021
    Review
16. Cytokines that Modulate the Differentiation of Th17 Cells in Autoimmune Uveitis.Journal of immunology research · 2021
    Review
17. Neuroinflammation Associated With Inborn Errors of Immunity.Frontiers in immunology · 2021
    Review
18. Laquinimod dampens IL-1β signaling and Th17-polarizing capacity of monocytes in patients with MS.Neurology(R) neuroimmunology & neuroinflammation · 2021
    Article
19. Bystander CD4Experimental & molecular medicine · 2020
    Review
20. Could the Heat Shock Proteins 70 Family Members Exacerbate the Immune Response in Multiple Sclerosis? An in Silico Study.Genes · 2020
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

Indexed as