Evidence map›Paper›PMID 27965663›Full record

ArticleFrontiers in immunology2016

Alteration in the Gut Microbiota Provokes Susceptibility to Tuberculosis.

Nargis Khan, Aurobind Vidyarthi, Sajid Nadeem, Shikha Negi, Girish Nair, Javed N Agrewala

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.

  1. Delayed-Type Hypersensitivity toInternational journal of molecular sciences · 2026
    Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Effects of dietaryJDS communications · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Status and outlook of pulmonary tuberculosis coinfection.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025
    Review
  14. Review
  15. Genetic diversity of single-celled microorganismCurrent research in microbial sciences · 2025
    Article
  16. Article
  17. Article
  18. Microbiota and Immunity during Respiratory Infections: Lung and Gut Affair.International journal of molecular sciences · 2024
    Review
  19. Article
  20. Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nargis KhanImmunology Division, CSIR-Institute of Microbial Technology , Chandigarh , India.
Aurobind VidyarthiImmunology Division, CSIR-Institute of Microbial Technology , Chandigarh , India.
Sajid NadeemImmunology Division, CSIR-Institute of Microbial Technology , Chandigarh , India.
Shikha NegiImmunology Division, CSIR-Institute of Microbial Technology , Chandigarh , India.
Girish NairImmunology Division, CSIR-Institute of Microbial Technology , Chandigarh , India.
Javed N AgrewalaImmunology Division, CSIR-Institute of Microbial Technology , Chandigarh , India.
Institute of Microbial Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The microbiota that resides in the gastrointestinal tract provides essential health benefits to the host. In particular, they regulate immune homeostasis. Recently, several evidences indicate that alteration in the gut microbial community can cause infectious and non-infectious diseases. Tuberculosis (TB) is the most devastating disease, inflicting mortality and morbidity. It remains unexplored, whether changes in the gut microbiota can provoke or prevent TB. In the current study, we have demonstrated the antibiotics driven changes in the gut microbial composition and their impact on the survival of

Indexed as

antibioticsfecal transplantgut microbiotaMycobacterium tuberculosistuberculosis

Identifiers

PMID27965663
PMCPMC5124573
OpenAlexW2558408679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.