Evidence map›Paper›PMID 27965658›Full record

ArticleFrontiers in microbiology2016

A Bioengineered Nisin Derivative, M21A, in Combination with Food Grade Additives Eradicates Biofilms of

Muireann K Smith, Lorraine A Draper, Pieter-Jan Hazelhoff, Paul D Cotter, R P Ross, Colin Hill

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Antibacterial efficacy ofJournal of food science and technology · 2023
    Article
  3. The Use of Natural Methods to Control Foodborne Biofilms.Pathogens (Basel, Switzerland) · 2022
    Review
  4. Review
  5. Frontiers in cellular and infection microbiology · 2022
    Review
  6. Article
  7. Review
  8. Review
  9. Broadening and Enhancing Bacteriocins Activities by Association with Bioactive Substances.International journal of environmental research and public health · 2020
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Muireann K SmithAPC Microbiome Institute, School of Microbiology, University College Cork Cork, Ireland.
Lorraine A DraperAPC Microbiome Institute, School of Microbiology, University College Cork Cork, Ireland.
Pieter-Jan HazelhoffWageningen University & Research Wageningen, Netherlands.
Paul D CotterAPC Microbiome Institute, School of Microbiology, University College CorkCork, Ireland; Teagasc Food Research CentreCork, Ireland.
R P RossAPC Microbiome Institute, School of Microbiology, University College Cork Cork, Ireland.
Colin HillAPC Microbiome Institute, School of Microbiology, University College Cork Cork, Ireland.
University College Cork · IEAPC Microbiome Institute · IEWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The burden of foodborne disease has large economic and social consequences worldwide. Despite strict regulations, a number of pathogens persist within the food environment, which is greatly contributed to by a build-up of resistance mechanisms and also through the formation of biofilms. Biofilms have been shown to be highly resistant to a number of antimicrobials and can be extremely difficult to remove once they are established. In parallel, the growing concern of consumers regarding the use of chemically derived antimicrobials within food has led to a drive toward more natural products. As a consequence, the use of naturally derived antimicrobials has become of particular interest. In this study we investigated the efficacy of nisin A and its bioengineered derivative M21A in combination with food grade additives to treat biofilms of a representative foodborne disease isolate of

Indexed as

bioengineeredbiofilmcinnamaldehydecitric acidcombinationsListeria monocytogenesnisin

Identifiers

PMID27965658
PMCPMC5127793
OpenAlexW2552369633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.