Evidence map›Paper›PMID 27965646›Full record

ArticleFrontiers in microbiology2016

Synthesis of Sphingolipids Impacts Survival of

Zachary D Moye, Kornelija Valiuskyte, Floyd E Dewhirst, Frank C Nichols, Mary E Davey

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Infection and immunity · 2026
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  5. Review
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  8. Journal of oral microbiology · 2025
    Article
  9. Inhibition of SARS-CoV-2 infection byMicrobiology spectrum · 2024
    Article
  10. Article
  11. Article
  12. An outer membrane vesicle specific lipoprotein promotesCurrent research in microbial sciences · 2024
    Article
  13. The multifaceted role of c-di-AMP signaling in the regulation ofFrontiers in cellular and infection microbiology · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Growth ofJournal of oral microbiology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zachary D MoyeDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville FL, USA.
Kornelija ValiuskyteDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville FL, USA.
Floyd E DewhirstDepartment of Microbiology, Forsyth Institute, CambridgeMA, USA; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, BostonMA, USA.
Frank C NicholsDivision of Periodontology, Department of Oral Health and Diagnostic Sciences, School of Dental Medicine, University of Connecticut, Farmington CT, USA.
Mary E DaveyDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville FL, USA.
University of Florida · USHarvard University · USUniversity of Connecticut · US

Funding

Mouse Oral Microbiome DatabaseR37DE016937 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI DEWHIRST, FLOYD E · 2011 to 2020
$8.6M
Comprehensive Training Program in Oral BiologyT90DE021990 · NIDCR · UNIVERSITY OF FLORIDA · PI Jose A Lemos · 2011 to 2026
$8.2M
Regulatory Mechanisms Controlling Expression of P. gingivalis Surface StructuresR01DE019117 · NIDCR · UNIVERSITY OF FLORIDA · PI DAVEY, MARY ELLEN · 2009 to 2019
$4.5M
Porphyromonas gingivalis lipids mediate bone loss through TLR2R01DE021055 · NIDCR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI NICHOLS, FRANK C · 2011 to 2015
$1.9M
NIDCR NIH HHS R01 DE019117NIDCR NIH HHS R01 DE021055NIDCR NIH HHS R37 DE016937NIDCR NIH HHS T90 DE021990
6 · The paper itself

Abstract

Bacteria alter the biophysical properties of their membrane lipids in response to environmental cues, such as shifts in pH or temperature. In essence, lipid composition determines membrane structure, which in turn influences many basic functions, such as transport, secretion, and signaling. Like other members of the phylum Bacteroidetes, the oral anaerobe

Indexed as

capsular polysaccharidesdihydroceramidespersistencesphingolipid biosynthesisstress response

Identifiers

PMID27965646
PMCPMC5126122
OpenAlexW2557362799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.