ReviewFrontiers in psychology2016
Can Psychological Expectation Models Be Adapted for Placebo Research?
Review in Frontiers in psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Trial
- Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial.Pain research & management · 2022Trial
- Trial
- Open-label placebo reduces fatigue in cancer survivors: a randomized trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Trial
- The Impact of Expectations and Framing on the course of Symptom Severity in Somatic Symptom Disorder-Ecological Momentary Assessment from the SOMA.SSD Study.International journal of behavioral medicine · 2026Article
- Effects of bogus genetic feedback on subjective and physiological responses to acute stress.Comprehensive psychoneuroendocrinology · 2026Article
- Placebo and nocebo phenomena in schizophrenia spectrum disorders: a narrative review on current knowledge and potential future directions.Psychological medicine · 2025Review
- Article
- Don't be a nocebo! Why healthcare organizations should value patients' expectations.Frontiers in psychology · 2024Article
- Creating and testing a questionnaire to predict immediate and strong positive responders to spinal manipulative therapy for non-specific low back pain. A pilot study.Chiropractic & manual therapies · 2023Article
- Comparison of indirect treatment methods in migraine prevention to address differences in mode of administration.Journal of comparative effectiveness research · 2023Review
- Review
- Placebo stimulates neuroplasticity in depression: implications for clinical practice and research.Frontiers in psychiatry · 2023Article
- Nocebo effects in visceral pain: concept and design of the experimental randomized-controlled pain study 'NoVis'.Frontiers in psychiatry · 2023Article
- Unraveling Negative Expectations and Nocebo-Related Effects in Musculoskeletal Pain.Frontiers in psychology · 2022Article
- Treatment expectations as a possible prognostic factor for DMARD response in rheumatoid arthritis: a prospective cohort study.Therapeutic advances in musculoskeletal disease · 2021Article
- Contextual factors of self-regulation in children and adolescents with chronic diseases - a qualitative analysis.BMC public health · 2020Article
- The potential role of illness expectations in the progression of medical diseases.BMC psychology · 2019Article
- Optimizing ExpectationsFrontiers in psychiatry · 2019Article
- Patients' Expectations Regarding Medical Treatment: A Critical Review of Concepts and Their Assessment.Frontiers in psychology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Placebo responses contribute substantially to the effect and clinical outcome of medical treatments. Patients' expectations have been identified as one of the major mechanisms contributing to placebo effects. However, to date a general theoretical framework to better understand how patient expectations interact with features of medical treatment has not been developed. In this paper we outline an expectation model that can be used as framework for experimental studies on both placebo and nocebo mechanisms. This model is based on psychological concepts of expectation development, expectation maintenance, and expectation change within the typical paradigms used in placebo research. This theoretical framework reflects the dynamic aspects of the interaction between expectations and medical treatment, and offers a platform to combine psychological and neurophysiological research activities. Moreover, this model can be used to identify important future research questions. For example, we argue that the dynamic processes of expectation maintenance vs. expectation changes are not sufficiently addressed in current research on placebo mechanisms. Therefore, the question about how to change and optimize patients' expectations prior to treatment should be a special focus of future clinical research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.